Mezym forte, pills, 80pcs

Composition

1 coated tablet contains:

Core:

Active ingredient: Pancreatin* – 116,66 – 134,61 mg with minimal activity:

• lipase — 3500 units Ph. Eig.
• amylase-4200 units Ph. Eig.
• protease-250 units Ph. Eig.

Auxiliary substances: microcrystalline cellulose (type 12), sodium carboxy-methyl starch (type A), colloidal anhydrous silicon dioxide, magnesium stearate.

Shell: talc, hypromellose, dye azorubin (E 122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E 171), macrogol 6000. * obtained from the pancreas of porcine glands

Pharmacological action

Pharmacotherapeutic group: digestive enzyme agent

ATX code: A 09 AA 02

Pharmacological properties

Pancreatin is a powder from the pancreas of pigs.

Pancreatic enzymes (lipase, amylase, protease) have proteolytic, amylolytic and lipolytic effects and contribute to the breakdown of proteins, fats, carbohydrates, improve the functional state of the gastrointestinal tract( GIT), thus normalizing the digestive processes. Active trypsin is supposed to inhibit feedback-type stimulated pancreatic secretion in the upper small intestine. The analgesic effect of pancreatin preparations, described in some cases, is associated with this effect. Pancreatic enzymes are not absorbed in the gastrointestinal tract, are excreted through the intestines, most of them are denatured under the action of digestive juices.

Indications

• Disorders of the enzyme (exocrine) function of the pancreas in diseases of the gastrointestinal tract accompanied by digestive disorders.
• To improve the digestion of food in patients with normal gastrointestinal function in case of nutritional errors.

Use during pregnancy and lactation

There are no data on the use of pancreatin during pregnancy and lactation. During pregnancy and lactation, the use of pancreatin by the attending physician is possible only if the intended benefit to the mother exceeds the possible risk to the fetus or child.

Recommendations for use

Contraindications

• hypersensitivity to any of the components of the drug.
• acute pancreatitis or exacerbation of chronic pancreatitis. However, it is possible to use in the phase of fading exacerbation with the expansion of the diet, if there are signs of digestive disorders;
• children under 3 years of age (for this dosage form).

Side effects

Possible side effects are listed below by descending frequency: very common (≥ 1/10), common (≥ 1/100, < 1/10), uncommon (≥ 1/1000, < 1/100), rare (≥ 1/10000, < 1/1000), very rare (

Immune system disordersVery rare: immediate allergic reactions. Frequency unknown: possible allergic reactions to the components of the drug (see the section “Composition”).

Disorders of the gastrointestinal tractVery rare: hypersensitivity of the gastrointestinal tract (for example, diarrhea, epigastric discomfort, nausea).

Interaction

It is possible to reduce the absorption of folic acid, which may require additional intake when used simultaneously with pancreatin. The effect of hypoglycemic agents for oral use (acarbose, miglitol) may decrease when used simultaneously with drugs containing digestive enzymes that break down carbohydrates (for example, amylase).

How to take, course of use and dosage

The dose of Mezym ® forte is determined individually depending on the degree of digestive disorders.

Adults: take 1-2 tablets before meals inside, without chewing and with water (the effectiveness of the drug Mezym ® forte may decrease with chewing, and pancreatic enzymes may irritate the oral mucosa when released).

If necessary, take an additional 2-4 tablets during meals.

In cases where higher doses of pancreatin are required, a doctor should be consulted to prescribe a higher dosage depending on the symptoms (for example, a decrease in the severity of steatorrhea, abdominal pain).

The duration of treatment can vary from several days (in case of digestive disorders due to errors in the diet) to several months or even years (if permanent replacement therapy is required).

In children, the drug is used as prescribed by a doctor.

Overdose

No cases of overdose were reported.

Description

pink, flat-cylindrical coated tablets with almost flat-parallel surfaces and beveled edges, with a characteristic smell.

Special instructions

Mezym forte contains active enzymes that, when released in the oral cavity, such as chewing, can damage the oral mucosa (up to the formation of ulcers). Therefore, the tablet must be swallowed whole.

Influence on the ability to drive vehicles and other mechanisms

The drug Mezym ® forte does not affect or has a slight effect on the ability to drive vehicles and mechanisms.

Form of production

Coated tablets. 20 tablets each in a contour cell package (blister) made of PVC/PE/PVDC/aluminum foil. 1,2,4 or 5 blisters with instructions for use of the drug in a cardboard box.

Storage conditions

At a temperature not exceeding 25 °C. Keep out of reach of children!

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Pancreatin

Dosage form

Tablets

Description

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Adults, Children over 3 years old, Children as prescribed by a doctor

Indications

Flatulence, Diet errors, Overeating, Diarrhea, Preparation for ultrasound and abdominal X-rays, Chronic pancreatitis