Pancreatin 25IU pills, 60pcs

Composition

Active ingredient:

pancreatin – 0.1 g (25 units).

Auxiliary substances:

milk sugar (lactose),

gelatin,

potato starch,

calcium stearate,

cellacephate (acetylphthalylcellulose),

titanium dioxide (titanium dioxide),

liquid paraffin (vaseline oil),

twin-80 (polysorbate),

dye azorubin (acid red 2C).

Pharmacological action

Compensates for the insufficiency of external secretory function of the pancreas, has a proteolytic, amylolytic and lipolytic effect.

Enzymes included in Pancreatin (lipase, amylase, trypsin, chymotrypsin) promote the breakdown of proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides.

Improves the functional state of the gastrointestinal tract, normalizes digestive processes.

Trypsin inhibits stimulated pancreatic secretion, exerting an analgesic effect.

Pancreatic enzymes are released from the dosage form in the alkaline environment of the small intestine, because they are protected from the action of gastric juice by the shell.

Indications

– replacement therapy for exocrine pancreatic insufficiency: chronic pancreatitis, pancreatectomy, as after irradiation, dyspepsia, cystic fibrosis;

– flatulence, diarrhea of non-infectious origin, roemheld syndrome (gastrocardiac syndrome);

– violation of digestion (condition after resection of the stomach and small intestine); to improve digestion in individuals with normal function of the gastrointestinal tract in the case of errors in the diet (consumption of fatty food, large quantities of food, irregular meals) with impaired chewing function, sedentary lifestyle, prolonged immobilization;

– preparation for x-ray and ultrasound of the abdominal cavity.

Contraindications

Hypersensitivity to the components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis, children under 6 years of age

Side effects

Allergic reactions. Rarely – diarrhea, constipation, a feeling of discomfort in the stomach, nausea (a causal relationship between the development of these reactions and the action of Pancreatin has not been established, since these phenomena relate to symptoms of external secretory pancreatic insufficiency).

With prolonged use in high doses, hyperuricosuria and hyperuricemia may develop. In cystic fibrosis, if the required dose of Pancreatin is exceeded, strictures (fibrous colonopathy) may develop in the ileocecal region in the ascending colon.

When using Pancreatin in high doses in children, perianal irritation and irritation of the oral mucosa may occur

Interaction

When using Pancreatin, it is possible to reduce the absorption of iron and folic acid.

Concomitant use of antacids containing calcium carbonate and / or magnesium hydroxide may reduce the effectiveness of Pancreatin.

How to take, course of use and dosage

Inside. The drug is taken during or after a meal, without chewing and washed down with a non-alkaline liquid (water, fruit juices).

The dose is determined individually depending on the degree of digestive disorders.

Adults usually take 2-4 tablets 3-6 times a day. The maximum daily dose is 16 tablets.

In children over 6 years of age, the drug is used as prescribed by a doctor. The dose is determined individually. Usually prescribed 1 tablet 3 times a day.

The duration of treatment can vary from several days (if the digestive process is disrupted due to dietary errors) to several months or years (if permanent replacement therapy is required).

Overdose

Symptoms: hyperuricosuria, hyperuricemia. Children have constipation.

Treatment: drug withdrawal, symptomatic therapy.

Special instructions

In cystic fibrosis, the use of Pancreatin in high doses is not recommended due to the increased risk of strictures (fibrous colonopathy).

The dose should be adequate to the amount of enzymes needed for fat absorption, taking into account the quality and quantity of food consumed.

Storage conditions

In a place protected from light and moisture, at a temperature not exceeding 20 °C

Shelf life

2 years

Active ingredient

Pancreatin

Dosage form

Tablets

Description

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Children over 3 years old, For adults

Indications

Overeating, Flatulence, Preparation for ultrasound and abdominal X-rays, Diet errors, Gastritis, Diarrhea, Chronic pancreatitis