Indications
Fever in infectious and inflammatory diseases. Pain syndrome of mild and moderate intensity of various genesis (including headache, migraine, toothache, neuralgia, myalgia, algodismenorrhea; pain from injuries, burns).
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Fever in infectious and inflammatory diseases. Pain syndrome of mild and moderate intensity of various genesis (including headache, migraine, toothache, neuralgia, myalgia, algodismenorrhea; pain from injuries, burns).
The drug is taken orally before meals in undiluted form, washed down with a large amount of liquid. Before use, the drug is thoroughly shaken. The frequency of reception is no more than 4 times a day with an interval of at least 4 hours.
The dose of paracetamol for children is calculated depending on age and body weight. A single dose of paracetamol is 10-15 mg/kg of body weight, daily-no more than 60 mg/kg of body weight.
For accurate dosage of the drug, depending on the proposed configuration, use a measuring spoon or a measuring syringe enclosed in the package.
Depending on the age, “Paracetamol for children” is prescribed in the following single doses::
– from 1 to 3 months — for symptomatic treatment of reactions to vaccination, a single dose of 2.5 ml of suspension is used. If necessary, the dose can be repeated, but not earlier than after 4 hours. If the child’s body temperature does not decrease after a second dose, you should consult a doctor. Further use of the drug in children of this age for the treatment of post-vaccination hyperthermia, as well as use in children aged 1-3 months for other indications is possible only under the supervision of a doctor. If it is necessary to use the drug for a premature baby aged 1-3 months, the drug is prescribed only on the recommendation of a doctor.
Single oral doses for children aged 6-12 years – 250-500 mg,1-5 years-120-250 mg, from 3 months to 1 year-60-120 mg, up to 3 months-10 mg/kg.
The duration of treatment is no more than 3 days as an antipyretic and no more than 5 days as an analgesic. Continuation of treatment with the drug is possible only after consulting a doctor!!!
Hypersensitivity, neonatal period (up to 1 month).
With caution. Renal and hepatic insufficiency, benign hyperbilirubinemia (including Gilbert’s syndrome), viral hepatitis, alcoholic liver damage, alcoholism, diabetes mellitus (for syrup), pregnancy, lactation, old age, early infancy (up to 3 months).
Active substance: paracetamol – 120 mg.
Auxiliary substances: avicel RC-591 [cellulose microcrystalline, sodium carmellose] – 50 mg, xanthan gum (xanthan gum) – 7.5 mg, methyl parahydroxybenzoate (nipagin) – 5 mg, propylene glycol – 1 mg, sucrose (sugar) – 1650 mg, glycerol (glycerin) – 630 mg, sorbitol (sorbitol food) – 1128,75 mg, orange flavor or flavoring strawberry – 6.5 mg, water (purified water) up to 5 ml.
Active ingredient: paracetamol – 120 mg. Auxiliary substances: avicel RC-591 [cellulose microcrystalline, sodium carmellose] – 50 mg, xanthan gum (xanthan gum) – 7.5 mg, methyl parahydroxybenzoate (nipagin) – 5 mg, propylene glycol – 1 mg, sucrose (sugar) – 1650 mg, glycerol (glycerin) – 630 mg, sorbitol (sorbitol food) – 1128,75 mg, orange flavor or flavoring strawberry – 6.5 mg, water (purified water) up to 5 ml.
Analgesic-antipyretic. It has analgesic, antipyretic and weak anti-inflammatory effects. The mechanism of action is associated with inhibition of prostaglandin synthesis, a predominant effect on the center of thermoregulation in the hypothalamus.
Fever in infectious and inflammatory diseases. Pain syndrome of mild and moderate intensity of various genesis (including headache, migraine, toothache, neuralgia, myalgia, algodismenorrhea; pain from injuries, burns).
Hypersensitivity, neonatal period (up to 1 month).
With caution. Renal and hepatic insufficiency, benign hyperbilirubinemia (including Gilbert’s syndrome), viral hepatitis, alcoholic liver damage, alcoholism, diabetes mellitus (for syrup), pregnancy, lactation, old age, early infancy (up to 3 months).
From the digestive system: rarely-dyspeptic phenomena, with prolonged use in high doses – hepatotoxic effect.
From the hematopoietic system: rarely-thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis.
Allergic reactions: rarely – skin rash, pruritus, urticaria.
Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, flumecinol, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, which causes the possibility of developing hepatotoxic effects in small overdoses. Microsomal oxidation inhibitors (including cimetidine) reduce the risk of hepatotoxic effects. Concomitant long-term use of high-dose paracetamol and salicylates increases the risk of developing kidney or bladder cancer. The combination with chloramphenicol leads to an increase in the toxic properties of the latter. Increases the effect of indirect anticoagulants and reduces the effectiveness of uricosuric drugs. Long-term use of barbiturates reduces the effectiveness of paracetamol. Myelotoxic drugs increase the manifestations of paracetamol hematotoxicity. Ethanol contributes to the development of acute pancreatitis. Long-term concomitant use of paracetamol and nonsteroidal anti-inflammatory drugs increases the risk of developing” analgesic ” nephropathy and renal papillary necrosis, the onset of end-stage renal failure. Diflunisal increases the plasma concentration of paracetamol by 50% – the risk of developing hepatotoxicity.
The drug is taken orally before meals in undiluted form, washed down with a large amount of liquid. Before use, the drug is thoroughly shaken. The frequency of reception is no more than 4 times a day with an interval of at least 4 hours. The dose of paracetamol for children is calculated depending on age and body weight. A single dose of paracetamol is 10-15 mg/kg of body weight, daily-no more than 60 mg/kg of body weight. For accurate dosage of the drug, depending on the proposed configuration, use a measuring spoon or a measuring syringe enclosed in the package.
Depending on the age, “Paracetamol for children” is prescribed in the following single doses: : – from 1 to 3 months — for symptomatic treatment of reactions to vaccination, a single dose of 2.5 ml of suspension is used. If necessary, the dose can be repeated, but not earlier than after 4 hours. If the child’s body temperature does not decrease after a second dose, you should consult a doctor. Further use of the drug in children of this age for the treatment of post-vaccination hyperthermia, as well as use in children aged 1-3 months for other indications is possible only under the supervision of a doctor. If it is necessary to use the drug for a premature baby aged 1-3 months, the drug is prescribed only on the recommendation of a doctor. Single oral doses for children aged 6-12 years – 250-500 mg,1-5 years-120-250 mg, from 3 months to 1 year-60-120 mg, up to 3 months-10 mg / kg. The duration of treatment is no more than 3 days as an antipyretic and no more than 5 days – as an analgesic. Continuation of treatment with the drug is possible only after consulting a doctor!!!
Symptoms: during the first 24 hours after ingestion – pallor of the skin, nausea, vomiting, anorexia, abdominal pain; impaired glucose metabolism, metabolic acidosis. Symptoms of impaired liver function may appear 12-48 hours after an overdose. In severe overdose – liver failure with progressive encephalopathy, coma, death; acute renal failure with tubular necrosis (including in the absence of severe liver damage); arrhythmia, pancreatitis. Hepatotoxic effect in adults manifests itself when taking 10 g or more. Treatment: use of SH-group donors and glutathione – methionine synthesis precursors within 8-9 hours after overdose and acetylcysteine-within 8 hours. The need for additional therapeutic measures (further use of methionine, intravenous use of acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as on the time elapsed after taking it.
It is used with caution in patients with impaired liver and kidney function, with benign hyperbilirubinemia, as well as in elderly patients.
With prolonged use of paracetamol, it is necessary to monitor the picture of peripheral blood and the functional state of the liver.
It is used for the treatment of premenstrual tension syndrome in combination with pamabrom (a diuretic, a derivative of xanthine) and mepyramine (a histamine H1-receptor blocker).
Oral suspension
Paracetamol
suspension for oral use
Children over 3 months of age
SARS, Flu, and Cold indications
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