Pentaflucin granules 5g sachets, 5pcs

Composition

1 sachet contains

Active ingredients:

• paracetamol 500 mg,
• ascorbic acid 200 mg,
• diphenhydramine 20 mg,
• rutin 20 mg

Pharmacological action

Pentaflucin is a combined drug that has antipyretic and anti-inflammatory effects. Its action is due to the active substances included in the composition:

• Paracetamol has an antipyretic and analgesic effect. Non-narcotic analgesic, blocks COX 1 and COX 2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX, which explains the almost complete absence of an anti-inflammatory effect.
• Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, and increases the body’s resistance.
• Diphenhydramine has antihistamine and anti-inflammatory, soothing and hypnotic effects.
• Rutosine reduces the permeability and fragility of capillaries, has antioxidant properties.

Indications

Hyperthermia in colds and other infectious and inflammatory diseases.

Use during pregnancy and lactation

Contraindicated: pregnancy and lactation.

Use in children.

Contraindicated: children under 16 years of age.

Contraindications

Hypersensitivity, renal and/or hepatic insufficiency, blood diseases with a tendency to hemorrhage, glucose-6-phosphate dehydrogenase deficiency, pregnancy, lactation, children (up to 16 years).

Side effects

Possible drowsiness and allergic skin reactions (rash, itching, urticaria), nausea, vomiting, headache, general weakness, dizziness.

Rarely-thrombocytopenia, leukopenia, agranulocytosis.

With prolonged use in high doses, hepatotoxic and nephrotoxic effects are possible.

Interaction

The combination of the drug with barbiturates, anticonvulsants, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes should be avoided.

How to take, course of use and dosage

Pentaflucin is taken orally after meals,1 packet 3-4 times a day for 3-5 days. 1 package of Pentaflucine is dissolved in 1/2 cup of hot water (a slight sediment in a glass is allowed).

Apply a freshly prepared solution.

Overdose

Symptoms: nausea, vomiting, stomach pain, after 1-2 days – liver failure, encephalopathy, coma.

Treatment: induce vomiting, gastric lavage, use of adsorbents (activated charcoal), symptomatic therapy (use of methionine, acetylcysteine).

Special instructions

Do not combine the drug with the use of ethanol in order to avoid toxic liver damage.

Influence on the ability to drive motor vehicles and manage mechanisms

During the treatment period, it is necessary to refrain from driving vehicles and engaging in potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Pentaflucine. Granules for the preparation of an oral solution

Storage conditions

In a dry place, protected from light

Shelf life

2 years

Active ingredient

Paracetamol, Ascorbic Acid, Rutoside, Diphenhydramine, Calcium Gluconate

Dosage form

solution for oral use

Description

For adults

Indications

Cold, Flu