PlacesMidin-Sense Daily solution for external use spray bottle without cannula, 50ml

Composition

>1 ml of the drug contains: Active ingredients:  Octenidine Dihydrochloride 1.0 Mgphenoxyethanol 20.0 MGM Auxiliary Substances:  Sodium Chloride 0.5 mg Coconut Oil Fatty Acid Propyl Betainamide (Cocamidopropyl betaine) 3.0 mg Sodium gluconate 4.0 mg Glycerol anhydrous 0.05 M sodium hydroxide solution or 0.05 M hydrochloric acid solution up to pH 5.0-7.0 Water for injection up to 1 ml

Pharmacological action

Antiseptic agent. Mesta Midin-sens has a wide spectrum of antimicrobial action, fungicidal and virucidal activity due to the hydrophobic interaction of octenidine dihydrochloride and phenoxyethanol with the cytoplasmic membranes of pathogenic microorganisms. The spectrum of antimicrobial activity covers spore and asporogenic microflora, gram-positive and gram-negative bacteria (aerobic and anaerobic), fungi of the genus dermatophytes and candida, lipophilic viruses, mycoplasmas, ureaplasmas. Resistance does not develop with short-term or long-term use of Mesta Midin-sens. The drug has no toxic effect and is practically not absorbed through the mucous membranes, skin and wound surfaces, destroys microorganisms without damaging tissue cells. The use of the drug promotes the healing of wounds, burns.

Indications

– Treatment of skin and mucous membranes in pediatric, surgical and obstetric-gynecological practice, in traumatology, proctology, dermatovenerology, otolaryngology, dentistry. – For treatment of wound and burn surfaces. – For the prevention of foot mycosis and interdigital mycosis. In children’s practice without age restrictions.

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation is possible if the intended benefit to the mother exceeds the possible risk to the fetus or child. Pregnancy There are limited data on the use of the drug in pregnant women (from 300 to 1000 pregnant women, gestational age ≥ 12 weeks), which indicate that the drug does not affect the development of congenital anomalies and its toxic effect on the embryo/fetus. Animal studies have shown no signs of reproductive toxicity. Breast-FEEDINGAS octenidine dihydrochloride is not absorbed or is absorbed in very small amounts, it is assumed that it does not pass into breast milk. Phenoxyethanol is rapidly and almost completely absorbed and excreted almost entirely as an oxidized product by the kidneys, so its accumulation in breast milk is unlikely. As a precautionary measure, it is recommended not to treat the surface of the mammary glands with Mesta Midin-sense immediately before feeding. Before using the drug during pregnancy and lactation, you should consult your doctor.

Contraindications

Hypersensitivity to the components of the drug. Do not use for washing the abdominal cavity (for example, during surgery), in the area of the eardrum and for instillation into the bladder.

Side effects

Adverse events (AES) are distributed according to the frequency of occurrence. The following criteria were used to assess frequency: very common (≥1/10); common (≥1/100, <1/10); uncommon (≥1/1000, <1/100); rare (≥1/10000, <1/1000); very rare (Within each group, AES frequencies are arranged in descending order of severity. General disorders and reactions at the application site: Rarely: burning, redness, itching, heat sensation at the application site. Very rare: contact allergic reaction, such as temporary redness at the site of application. When rinsing the mouth, a bitter taste may appear. The following side effects may occur-swelling, tightness, pain, blisters, eczema in the application area. Paediatric population The frequency, type and severity of adverse reactions in children are the same as in adults. If used improperly (for example, injections into tissues), edema and tissue damage up to necrosis may occur. If you experience any of the side effects listed in the instructions, or they get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Do not use in conjunction with iodine-containing antiseptics due to the possibility of a pronounced change in skin color in adjacent areas from brown to purple. If you are using the above or other medications (including over-the-counter medications), please consult your doctor before using the drug.

How to take, course of use and dosage

Surgery, traumatology, proctology, pediatrics for preventive and curative purposes irrigate the skin and mucous membranes. The affected surface must be treated completely. On hard-to-reach areas, the drug can be applied by spraying. The exposure time is at least 1-2 minutes. Obstetrics, gynecologys Anation of the birth passagesanation of the birth passageis carried out by irrigation using a cannula, undiluted solution 1 time a day, for 5-7 days. Treatment of the surgical fieldbefore surgical intervention, the surgical field is treated with a sterile cloth, abundantly moistened with the drug, or irrigated with a cannula. The surface must be treated twice. Treatment of the hands of an obstetrician-gynecologist Before using the drug, the hands and forearms are thoroughly washed with warm water and neutral soap for 2 minutes, dried with a sterile gauze cloth. On thoroughly washed and dried hands, apply the drug (at least twice 3-5 ml), the exposure time is 5 minutes. Sterile gloves should only be worn on dry hands. Treatment of teats of milk jelliesfor the treatment of teats for preventive purposes and for the treatment of cracks, the teats are treated with the drug immediately after feeding. Immediately before the next feeding of the child, it is necessary to wipe the mammary glands with a cloth moistened with boiled water. Prevention of sexually transmitted diseases (STDs) For the prevention of STDs, the drug is used no later than 30 minutes after sexual intercourse. It is necessary to carry out abundant irrigation or wiping with a moistened cotton swab of the skin and mucous membranes of the external genitalia. Treatment of skin and mucous membranes in newborns detey Mesta Midin-sens is used undiluted for the treatment of umbilical wounds, before setting venous cannulas, central venous catheters, peripheral catheters, by irrigation or by wiping with a swab abundantly moistened with antiseptic. Treatment of postoperative sutures is carried out by irrigation with a cannula or by wiping with a swab, abundantly moistened with the drug,2 times a day for 5-7 days. Otolaryngologyadults. Irrigation of the oral cavity with a cannula by double pressing,3-4 times a day. To rinse the mouth and pharynx, it is recommended to use 20 ml of the drug for 20 seconds. It is possible to dilute the drug in a ratio of 1: 1 (1 part of the Place-Midina-sens and 1 part of drinking water). Oral and pharyngeal rinsing is recommended only for patients who can rinse their mouth out on their own. Children. Children aged 3-6 years: treatment of the oral cavity with a swab, abundantly moistened with the drug (3-5 ml),3-4 times a day. Children aged 7-14 years: mouthwash (5-7 ml),3-4 times a day. It is possible to dilute the drug in a ratio of 1: 1 (1 part of Mesta Midine-sens and 1 part of drinking water). Children over 14 years of age: irrigation of the oral cavity with a single push of a cannula,3-4 times a day. It is recommended to use 10 ml of the drug for 20 seconds to clean the oral and pharyngeal cavities. It is possible to dilute the drug in a ratio of 1: 1 (1 part of Mesta Midine-sens and 1 part of drinking water). The duration of therapy is from 4 to 7 days, depending on the time of remission. Dentistry. Oral and pharyngeal lavage is recommended only for patients who can rinse their mouth on their own. In this case,20 ml of the drug is used to rinse the mouth and pharynx for 20 seconds. The contact time should not exceed 1 minute. If the patient is unable to rinse on their own, you can wipe the mouth and throat with a moistened swab. In this case, the contact time should not exceed 2 minutes. In any case, make sure that the drug does not enter the respiratory tract. It is possible to dilute the drug in a ratio of 1: 1 (1 part of the Place-Midina-sens and 1 part of drinking water). If there is no improvement after treatment, or if the symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the method of use and in the doses indicated in the instructions for use. Duration of application is not more than 14 days.

Overdose

When using the drug in accordance with the instructions for use, overdose is unlikely. In case of overdose with topical application, wash the treated areas with a large amount of Ringer’s solution. In case of accidental ingestion of the drug, symptomatic therapy is indicated.

Special instructions

Avoid contact with eyes. In case of accidental ingestion of a significant amount of the drug in the stomach, it should be washed with plenty of water and take activated charcoal. Oral use of Mestamidine-sens should be avoided. In order to prevent tissue damage, it is forbidden to inject the drug into the tissue under pressure, especially with a syringe. It is always necessary to provide drainage. Influence on the ability to drive vehicles and mechanisms The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Solution for local and external use

Storage conditions

Store at a temperature not exceeding 25 ° C. Keep out of reach of children.

Shelf

life is 3 years. Do not use after the expiration date!

Active ingredient

Octenidine Dihydrochloride, Phenoxyethanol

Dosage form

spray for external use