Polynadim, eye drops, 10ml

Composition

Eye drops in the form of a clear, slightly colored liquid.

Auxiliary substances:

boric acid (15 mg / ml),

water-soluble methylcellulose (1.5 mg / ml),

sodium tetraborate decahydrate (500 mcg / ml),

disodium edetate (600 mcg/ml),

d/i water (up to 1 ml).

Pharmacological action

Polinadim eye drops are a combination drug used topically.

One of the components, diphenhydramine (diphenhydramine), has a pronounced anti-allergic effect, blocks histamine H1 receptors, reducing itching, swelling, and lacrimation.

The second Active ingredient, naphazoline (known as naphthyzine), narrows peripheral blood vessels for a long time, and when used topically, reduces inflammation and swelling.

Indications

• acute allergic conjunctivitis (including pollinous conjunctivitis);
• conjunctivitis with drug allergy;
• infectious eye diseases with an acute allergic component (as an additional agent).

Use during pregnancy and lactation

The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother exceeds the possible risk to the fetus or child.

Use in children

Contraindication: children under 2 years of age.

Contraindications

• Conjunctival xerosis (dry keratoconjunctivitis, Sjogren’s syndrome).
• Concomitant use with MAO inhibitors for a period of 10 days after their withdrawal.
• Angle-closure glaucoma.
• Pregnancy.
• Lactation period.
• Children under 2 years of age.
• Hypersensitivity to the components of the drug.

The drug should be used with caution when: :

• Thyrotoxicosis.
• Arterial hypertension.
• Atherosclerosis.
• Arrhythmias.
• Chronic rhinitis.
• Bronchial asthma.
• Adrenal adenoma.
• In elderly patients.
• With benign prostatic hyperplasia with the presence of residual urine.

Side effects

Local reactions may develop – conjunctival irritation, burning, redness, itching in the eye area, visual acuity disorders, increased intraocular pressure, pupil dilation, pain in the eye area, dryness of the nasal mucosa. After discontinuation of the drug, the reactions pass.

One case of corneal opacity was recorded (Polinadim eye drops were instilled at least 10 times a day for a week), the symptoms also disappeared after the eye drops were discontinued.

In rare cases (mainly in children and elderly patients), an increased heart rate, pallor of the skin, pain in the heart area, increased blood pressure, increased sweating, headache, trembling, drowsiness, dizziness, nausea may develop.

Interaction

When used concomitantly with tricyclic antidepressants, the vasoconstrictor effect of naphazoline may be enhanced.

The use of MAO inhibitors simultaneously with naphazoline or within 10 days after their withdrawal may lead to a hypertensive crisis.

How to take, course of use and dosage

In the acute period, adults are instilled 1 drop into the conjunctival sac every 3 hours until the irritation and swelling of the eye decreases. Continue 1 drop 2-3 times a day-until the clinical symptoms disappear.

Children over 2 years of age are instilled 1-2 drops per day.

It is not recommended to use Polinadim for more than 5 days without a doctor’s recommendation.

If symptoms of conjunctival irritation persist for 72 hours, stop using Polinadim eye drops and consult an ophthalmologist.

Overdose

With topical application of the drug, overdose is unlikely.

Symptoms:  in children under 6 years of age, prolonged and frequent use may lead to CNS depression, hypothermia, prolonged mydriasis, increased blood pressure, and tachycardia.

Treatment:  conducting symptomatic therapy.

Special instructions

Do not use the drug more often than every 3 hours (for 5 days).

The drug is not intended for oral use or injection.

In case of symptoms that indicate systemic absorption, it is necessary to stop using the drug.

For allergy symptoms and during treatment with the drug, it is not recommended to use soft contact lenses. If their use is necessary, the lenses should be removed before instillation and installed back, no earlier than 15 minutes.

Influence on the ability to drive motor vehicles and manage mechanisms

Since visual clarity is temporarily impaired after instillation, patients should refrain from driving vehicles and activities that require visual clarity immediately after using the drug.

Form of production

Polinadim. Eye drops.

Storage conditions

Store in a dark place at a temperature of 15-25 °C (do not freeze)

Shelf life

2 years

Active ingredient

Diphenhydramine, Naphazoline

Conditions of release from pharmacies

By prescription

Dosage form

eye drops

Description

For adults as prescribed by a doctor, Children over 2 years of age

Indications

Hay Fever, Allergies, Eye Infections