Rhinostop, nasal drops 0.05%, 10ml

Composition

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1 ml of drops contains:

Active ingredient:

xylometazoline (in the form of hydrochloride) 0.0005 g;

Auxiliary substances:

benzalkonium chloride;

disodium salt of ethylenediaminetetraacetic acid (trilon B);

single-substituted potassium phosphate;

double-substituted sodium phosphate;

sodium chloride;

purified water.

Pharmacological action

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes narrowing of the blood vessels of the nasal mucosa, thus eliminating edema and hyperemia of the nasal mucosa, restores patency of the nasal passages, facilitates nasal breathing.

The effect of the drug occurs a few minutes after its application and lasts up to 10 hours.

Pharmacokinetics

When applied topically, the drug is practically not absorbed, so its concentration in blood plasma is very low (it is not determined by modern analytical methods).

Indications

It is used for acute respiratory diseases with rhinitis (runny nose), acute allergic rhinitis, sinusitis, otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa), runny nose with allergies and colds.

Preparation of the patient for diagnostic manipulations in the nasal passages.

Use during pregnancy and lactation

During pregnancy and lactation, Rhinostop should be used only after careful assessment of the risk-benefit ratio for the mother and fetus, and it is not allowed to exceed the recommended doses.

Contraindications

Hypersensitivity to xylometazoline and other components of the drug, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, surgical interventions on the meninges (in the anamnesis), conditions after transsphenoidal pituitary surgery, children (up to 2 years – for 0.05% spray, up to 6 years for 0.1% spray), pregnancy.

Do not use in therapy with monoamine oxidase inhibitors and tricyclic antidepressants (including the period of 14 days after their withdrawal).

Side effects

With frequent and / or prolonged use: mucosal irritation, burning, tingling, sneezing, dryness of the nasal mucosa, hypersecretion.

Rarely:  swelling of the nasal mucosa (more often with prolonged use), palpitations, cardiac arrhythmias, increased blood pressure, headache, vomiting, sleep disorders, visual disturbances.

With prolonged use in high doses:  depressive state.

How to take, course of use and dosage

Apply topically for 7-14 days.

The dosage depends on the dosage form used and the patient’s age.

Form of production

nasal drops

Storage conditions

In a dark place, at a temperature of 0-25 °C

Shelf life

3 years

Active ingredient

Xylometazoline

Dosage form

nasal drops

Description

Children’s forms