Terbinafin-MFF pills 250mg, 10pcs

Composition

>of 1 tab. contains: Active ingredients: terbinafine hydrochloride – 281 mg, which corresponds to the content of terbinafine-250 mg. Auxiliary substances: lactose monohydrate (milk sugar) – 102.8 mg, sodium carboxymethyl starch (type A) – 25.8 mg, hypromellose-12.9 mg, colloidal silicon dioxide-3.2 mg, magnesium stearate-4.3 mg

Pharmacological action

Antifungal agent of the allylamine group. It has an effect by suppressing squalene oxidase in the cell membrane of the fungus. This leads to a deficiency of ergosterol and an intracellular accumulation of squalene, which causes cell death of the pathogen.

It has a fungicidal effect on dermatophytes, mold and some dimorphic fungi, yeast and yeast-like fungi. It can act fungistatically on some types of yeast fungi.

Active against pathogens of dermatomycosis (Trichophyton /including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum/, also Microsporum canis and Epidermophyton floccosum); yeast-like fungi of the genus Candida (mainly Candida albicans); pathogen of multicolored lichen (Malassezia furfur).

Indications

For oral use: fungal skin lesions caused by dermatophytes-trichophytosis, epidermophytosis, microsporia, fungal nail lesions (onychomycosis), candidiasis.

For external use: fungal skin lesions caused by dermatophytes, candidiasis; multicolored lichen.

Contraindications

Hypersensitivity to terbinafine.

Side effects

From the digestive system:  nausea, anorexia, mild abdominal pain, diarrhea, impaired or lost taste, cholestasis, jaundice, hepatitis.

Allergic reactions:  skin rash; rarely-arthralgia, myalgia, erythema multiforme, Stevens-Johnson syndrome.

From the central nervous system:  headache.

From the hematopoietic system:  neutropenia, thrombocytopenia.

Local reactions:  hyperemia, itching, burning sensation.

Interaction

Drugs that induce microsomal liver enzymes increase the clearance of terbinafine; drugs that inhibit microsomal liver enzymes decrease the clearance of terbinafine.

How to take, course of use and dosage

Inside adults-250 mg / day in 1 or 2 doses.

The duration of treatment depends on the indications and severity of the infection: for skin lesions-2-4 weeks, for nail lesions-from 6 weeks. up to 4 months or more. Children with a body weight of more than 40 kg – 250 mg / day,20-40 kg-125 mg/day, up to 20 kg-62.5 mg / day.

Topically apply 1-2 times / day for 1-2 weeks.

Special instructions

Terbinafine should be used with caution for oral use in patients with impaired liver and/or kidney function, as well as in the elderly.

Active ingredient

Terbinafine

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

Children as prescribed by a doctor, Adults as prescribed by a doctor, Children over 2 years of age

Indications

Nail Fungus, Toenail Fungus, Scalp Fungus, Thrush