Tetracycline, pills 100mg, 20pcs

Composition

of 1 tab. tetracycline hydrochloride 100 mg

Pharmacological action

Broad-spectrum antibiotic. It has a bacteriostatic effect by suppressing the protein synthesis of pathogens.

Active against aerobic gram-positive bacteria: Staphylococcus spp. (including penicillinase-producing strains), Streptococcus spp. ; gram-negative bacteria: Neisseria gonorrhoeae, Bordetella pertussis, Enterobacter spp., Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp. ; Anaerobic bacteria: Clostridium spp.

It is also active against Rickettsia spp., Chlamydia spp., Mycoplasma spp., Spirochaetaceae.

Pseudomonas aeruginosa, Proteus spp., Serratia spp., most strains of Bacteroides fragilis, most fungi, and small viruses are resistant to tetracycline.

Indications

Infectious and inflammatory diseases caused by tetracycline-sensitive microorganisms, including pneumonia, bronchitis, pleural empyema, sore throat, cholecystitis, pyelonephritis, intestinal infections, endocarditis, endometritis, prostatitis, syphilis, gonorrhea, brucellosis, rickettsiosis, purulent soft tissue infections, osteomyelitis; trachoma, conjunctivitis, blepharitis; acne.

Prevention of postoperative infections.

Contraindications

Liver failure, leukopenia, mycoses, children under 8 years of age, pregnancy, lactation (breastfeeding), hypersensitivity to tetracycline.

Side effects

From the digestive system:  nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, dry mouth, glossitis, discoloration of the tongue, esophagitis, transient increase in the activity of hepatic transaminases, alkaline phosphatase, bilirubin concentration, residual nitrogen.

From the central nervous system:  dizziness, headache.

From the hematopoietic system:  neutropenia, thrombocytopenia, hemolytic anemia.

Allergic reactions:  skin rash, pruritus, eosinophilia, angioedema.

Dermatological reactions:  photosensitization.

Effects due to chemotherapeutic action:  candidal stomatitis, candidal vulvovaginitis, intestinal dysbiosis.

Local reactions:  soreness at the injection site.

Other services:  hypovitaminosis of B vitamins.

Interaction

Preparations containing metal ions (antacids, preparations containing iron, magnesium, calcium) form inactive chelates with tetracycline, and therefore it is necessary to avoid their simultaneous use.

It is necessary to avoid combination with penicillins, cephalosporins that have a bactericidal effect and are antagonists of bacteriostatic antibiotics (including tetracycline).

Concomitant use of tetracycline with retinol may lead to the development of intracranial hypertension.

When used concomitantly with colestyramine or colestipol, there is a violation of the absorption of tetracycline.

How to take, course of use and dosage

Inside adults – 250-500 mg every 6 hours. Children older than 8 years – 25-50 mg/kg every 6 hours.

Externally applied several times a day, if necessary, apply a weak bandage.

Topically-3-5 times/day.

The maximum daily dose for adults when taken orally is 4 g.

Special instructions

With prolonged use, it is necessary to periodically monitor the functions of the kidneys, liver, and hematopoietic organs.

The use of tetracycline in children during the development of teeth can lead to an irreversible change in their color.

During the treatment period, vitamins of group B, K, and brewer’s yeast should be used to prevent hypovitaminosis.

Tetracycline should not be taken simultaneously with milk and other dairy products, because the absorption of the antibiotic is disrupted.

Active ingredient

Tetracycline

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

For adults by doctor’s prescription, Children by doctor’s prescription, Children over 8 years of age

Indications

Pneumonia, Infectious Diseases, Intestinal Infections, Cholecystitis, Whooping Cough, Acne, Tracheitis, Bronchitis, Tonsillitis, Boils, Stomatitis, Pharyngitis