Tsipromed, eye drops 0.3%, 5ml

Composition

Eye drops 0.3% in the form of a clear solution from colorless to pale yellow.

1 ml – ciprofloxacin (in the form of hydrochloride) 3 mg.

Auxiliary substances:

benzalkonium chloride,

sodium edetate,

lactic acid,

sodium chloride,

sodium hydroxide,

d/i water.

Pharmacological action

Ciprofloxacin is an antimicrobial drug from the group of fluoroquinolones, has a wide spectrum of antibacterial action, has a bactericidal effect.

The drug inhibits the enzyme DNA gyrase of bacteria, as a result of which DNA replication and synthesis of bacterial cell proteins are disrupted. Ciprofloxacin acts both on multiplying microorganisms and on dormant ones.

The spectrum of antibacterial action of ciprofloxacin include gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp. Proteus spp. (indolpologitiona and Industrialny), Morganella morganii, Citrobacter spp., Klebsiella spp. Enterobacter spp. Vibrio spp. Campylobacter spp. Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida, Pseudomonas spp., Gardnerella spp. Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp. Chlamidia spp.

Gram-positive microorganisms are also susceptible to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, St. agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes. The drug is low-toxic.

Indications

Infectious and inflammatory diseases of the eye and its appendages caused by microorganisms sensitive to the drug:

• Acute and subacute conjunctivitis.
• Keratitis.
• Anterior uveitis.
• Blepharitis and other inflammatory diseases of the eyelids.
• Dacryocystitis.

Prevention and treatment of infectious complications in injuries of the eye and its appendages and during operations on the eyeball.

Use during pregnancy and lactation

Tsipromed is contraindicated for use during pregnancy. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.

Use in children

Contraindication: children under 1 year of age.

Contraindications

• pregnancy;
• lactation(breastfeeding);
• children under 1 year of age;
• hypersensitivity to the components of the drug or to other fluoroquinolones.

Side effects

Slight burning sensation within 1-2 minutes (immediately after instillation); itching, soreness, hyperemia of the eye mucosa, foreign body sensation in the eyes, unpleasant taste in the mouth immediately after instillation, decreased visual acuity, allergic reactions, eyelid edema, photophobia, lacrimation, appearance of white crystalline precipitate in patients with corneal ulcers, keratitis, keratopathy, appearance of spots or corneal infiltration, development of superinfection.

Interaction

Rastovor ciprofloxacin is incompatible with drugs with a pH value of 3-4, which are physically and chemically unstable.

How to take, course of use and dosage

Locally. The drug is instilled 1-2 drops in the conjunctival sac. The frequency of installations depends on the severity of the inflammatory process. For acute bacterial conjunctivitis, simple, scaly and ulcerative blepharitis, Cipromed is prescribed from 4 to 8 times a day, depending on the severity of the disease. The course of treatment is from 5 to 14 days. For keratitis, the drug is prescribed 1 drop at least 6 times a day, if there is a positive effect, the maximum course of treatment, depending on the severity of the corneal lesion, is 2-4 weeks. If the cornea is affected by Pseudomonas aeruginosa, Cipromed is prescribed as often as possible – at least 8-12 times a day for 1 drop. The course of treatment depends on the course of the disease and usually lasts about 2-3 weeks.

With anterior uveitis, the drug is instilled 8-12 times a day for 1 drop.

In acute dacryocystitis and canaliculitis, Cipromed is prescribed 6-12 times a day, in chronic cases-4-8 times a day for 1 drop.

For injuries to the eye and its appendages, Cipromed is prescribed for 1-2 weeks for the prevention of secondary infection,1 drop 4-8 times a day.

For the prevention of inflammatory diseases after surgical interventions with perforation of the eyeball, Tsipromed is prescribed 4-6 times a day for 1 drop for the entire postoperative period, usually from 5 days to 1 month.

Overdose

With accidental ingestion of Cipromed, there are no specific symptoms.

Symptoms may include nausea, vomiting, diarrhea, headache, fainting, and anxiety.

Treatment: it is necessary to ensure sufficient fluid intake, maintain the acidic reaction of the urine to prevent crystalluria. If necessary, conduct symptomatic therapy.

Special instructions

If the patient is wearing soft contact lenses, they should not use Cipromed, as the preservative can be deposited in soft contact lenses and have an adverse effect on the eye tissue.

You should remove the hard contact lenses before instilling the drug and put them on again only after 15 minutes.

When using other ophthalmic medications, the interval between their use should be at least 5 minutes.

Immediately after instillation of the drug, visual clarity may decrease and mental reactions may slow down, which may reduce the ability to actively participate in traffic, maintain cars, or perform work without support. To an even greater extent, this occurs when the drug is used simultaneously with alcohol.

Form of production

Eye drops.

Storage conditions

In a dark place, at a temperature not exceeding 25 °C (do not freeze)

Shelf life

2 years

Active ingredient

Ciprofloxacin

Conditions of release from pharmacies

By prescription

Dosage form

eye drops

Description

Children as prescribed by a doctor, Adults as prescribed by a doctor, Children over 15 years of age

Indications

Inflammatory Eye diseases, Blepharitis, Barley on the eye, Conjunctivitis, Eye Infections