Velafax, pills 37.5mg 28pcs

Composition

1 tablet contains venlafaxine (in the form of hydrochloride) 150 mg

Pharmacological action

Velafax, an antidepressant that is not chemically related to any class of antidepressants (tricyclic, tetracyclic or other), is a racemate of two active enantomers.

The mechanism of antidepressant action of the drug is associated with its ability to potentiate the transmission of a nerve impulse to the central nervous system.

Indications

Depression of various etiologies (treatment and prevention).

Contraindications

Hypersensitivity to the components of the drug;

concomitant use of MAO inhibitors;

severe renal and / or hepatic impairment (glomerular filtration rate, GFR less than 10 ml / min);

age up to 18 years (safety and efficacy for patients of this age group have not been proven);

established or suspected pregnancy;

lactation period

Use with caution in the case of a recent myocardial infarction, unstable angina, arterial hypertension, tachycardia, convulsive syndrome in the anamnesis, increased intraocular pressure, angle-closure glaucoma, manic condition in the anamnesis, predisposition to bleeding, with initially reduced body weight.

Side effects

Common symptoms: weakness, fatigue.

From the gastrointestinal tract: decreased appetite, constipation, nausea, vomiting, dry mouth, rarely — hepatitis.

From the side of metabolism: increased serum cholesterol, decreased body weight, sometimes-changes in the results of laboratory tests of liver function, hyponatremia, syndrome of insufficient secretion of antidiuretic hormone.

From the cardiovascular system: arterial hypertension, hyperemia of the skin, postural hypotension, tachycardia.

From the central nervous system: unusual dreams, dizziness, insomnia, increased excitability, paresthesia, stupor, increased muscle tone, tremor, yawning; sometimes-apathy, hallucinations, muscle spasms, serotonin syndrome, rarely-epileptic seizures, manic reactions, as well as symptoms resembling neuroleptic malignant syndrome.

From the genitourinary system: ejaculation disorders, erections, anorgasmia, dysuric disorders (mainly difficulties at the beginning of urination); sometimes-decreased libido, menorrhagia, urinary retention.

From the sensory organs: accommodation disorders, mydriasis, visual impairment; infrequently-impaired taste sensations.

From the skin: sweating; sometimes-photosensitivity reactions; rarely-erythema multiforme, Stevens-Johnson syndrome.

From the hematopoietic system: sometimes-hemorrhages in the skin (ecchymosis) and mucous membranes, thrombocytopenia; rarely-prolongation of bleeding time.

How to take, course of use and dosage

Inside, while eating.

The recommended initial daily dose of Velafax is 37.5 mg 2 times a day.

If after several weeks of treatment there is no significant improvement, the dose can be increased to 150 mg per day-75 mg 2 times a day.

Special instructions

Discontinuation of Velafax: as with other antidepressants, abrupt discontinuation of venlafaxine therapy, especially after high doses of the drug, may cause withdrawal symptoms, so it is recommended to gradually reduce the dose before discontinuing the drug.

The length of time required to reduce the dose depends on its value, the duration of therapy, as well as the individual sensitivity of the patient.

Form of production

Tablets

Storage conditions

Store in a dry place protected from light at a temperature of not more than 25 C.

Shelf

life is 3 years.

Active ingredient

Venlafaxine

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

For adults as directed by your doctor

Indications

Depression