Viferon, gel 36000me/g, 12g

Composition

1 g of gel for external and topical use contains the Active ingredient:

human recombinant Interferon alfa-2b 36000 IU;

excipients:

alpha-tocopherol acetate of 0.055 g,

benzoic acid 0,00128 g

of sodium tetraborate decahydrate 0,0018 g,

methionine 0,0012 g,

citric acid monohydrate 0.001 g

of sodium chloride 0.004 g,

the solution of human serum albumin 10% 0.02 g

distilled glycerin (glycerol) 0.02 g,

carmellose sodium 0.02 g,

ethanol 95% of 0.055 g,

purified water to 1 g.

Pharmacological action

Human recombinant Interferon alfa-2b has immunomodulatory, antiviral and antiproliferative properties. Suppresses replication of RNA and DNA-containing viruses. The immunomodulatory properties of interferon, such as an increase in the phagocytic activity of macrophages, an increase in the specific cytotoxicity of lymphocytes to target cells, determine its indirect antibacterial activity.

In the presence of the antioxidants alpha-tocopherol acetate, citric and benzoic acids, the specific antiviral activity of interferon increases, its immunomodulatory effect increases, which makes it possible to increase the effectiveness of the body’s own immune response to infectious agents.

The drug has a pronounced local immunomodulatory effect and contributes to an increase in locally formed antibodies of the secretory IgA class, which prevent the fixation and reproduction of pathogenic microorganisms on the mucous membranes, which provides a preventive effect of the drug for the prevention of viral and other diseases.

The gel base provides a prolonged action of the drug. Antioxidants included in the dosage form – alpha-tocopherol acetate, citric and benzoic acids have anti-inflammatory, membrane-stabilizing, regenerating properties, and also contribute to the preservation of the biological activity of human recombinant Interferon alfa-2b.

Indications

• – in the complex therapy of acute respiratory infections, including influenza, frequent and long-term acute respiratory infections, including those complicated by bacterial infection;- prevention of acute respiratory viral infections, including influenza; – in the complex therapy of recurrent stenosing laryngotracheobronchitis;— prevention of recurrent stenosing laryngotracheobronchitis— – in the complex therapy of acute and exacerbations of chronic recurrent herpetic infection of the skin and mucous membranes, including the urogenital form of herpetic infection;— in the complex therapy of herpetic cervicitis.

Use during pregnancy and lactation

Pregnancy and lactation are not contraindications for the use of the drug due to the very low absorption of the components.

During lactation, do not apply to the area of the nipples and areola.

Contraindications

Hypersensitivity to any of the components of the drug.

Side effects

In rare cases, allergic reactions (skin rashes, itching) may develop.

Interaction

The drug is well combined with all medications used in the treatment of the above diseases (antibiotics, chemotherapy drugs, glucocorticosteroids).

How to take, course of use and dosage

The drug is applied topically and topically.

In the complex therapy of acute respiratory infections, including influenza, long-term and frequent acute respiratory infections, including those complicated by bacterial infection:

A strip of gel no longer than 0.5 cm is applied to the pre-dried surface of the nasal mucosa and/or to the surface of the palatine tonsils 3-5 times a day. The duration of the course is 5 days, if necessary, the course can be extended.

Recurrent stenosing laryngotracheobronchitis:

A strip of gel no longer than 0.5 cm is applied to the surface of the palatine tonsils in the acute period of the disease 5 times a day. The course duration is 5-7 days.

A strip of gel no longer than 0.5 cm is applied to the surface of the palatine tonsils after an acute period 3 times a day. The course duration is 3 weeks.

Acute and chronic recurrent herpetic infection (when the first signs of the disease appear or during the period of harbingers):

A strip of gel with a length of no more than 0.5 cm is applied with a spatula or cotton swab/cotton swab to the previously dried affected surface 3-5 times a day. The course duration is 5-6 days. If necessary, the duration of the course is increased until the clinical manifestations disappear.

Herpetic cervicitis:

1 ml of gel is applied with a cotton swab to the surface of the cervix previously cleaned of mucus 2 times a day. The course duration is 7 days. If necessary, the duration of the course can be extended to 14 days.

Acute respiratory viral infections, including the flu:

During the period of rising morbidity, a strip of gel with a length of no more than 0.5 cm is applied to the previously dried surface of the nasal mucosa and/or to the surface of the palatine tonsils 2 times a day. The course duration is 2-4 weeks.

Recurrent stenosing laryngotracheobronchitis:

A strip of gel no longer than 0.5 cm is applied to the surface of the palatine tonsils using a spatula or cotton swab/cotton swab 2 times a day. The duration of the course is 3-4 weeks, the courses are repeated 2 times a year.

On the mucous membrane of the nasal cavity, the gel is applied after cleaning the nasal passages, on the surface of the palatine tonsils – 30 minutes after eating. When applying the gel to the palatine tonsils, do not touch the tonsils with a cotton swab, but only with gel, the gel flows down the surface of the tonsils independently. When applying the gel to the cervix, you should first remove mucus and secretions from the vaginal and cervical arches with a cotton or gauze swab.

When the gel is applied to the affected areas of the skin and mucous membranes, a thin film is formed after 30-40 minutes, on which the drug is again applied. If desired, the film can be peeled off or washed off with water before applying the product again.

Special instructions

There are no age restrictions for the use of the drug in gel form according to indications and in recommended doses.

Form of production

Gel.

Storage conditions

Store in a dry place, protected from light, at a temperature of 2-8 °C

Shelf life

1 year

Active ingredient

Interferon alfa-2b

Dosage form

gel for external use

Description

For children as prescribed by a doctor, Nursing mothers, For adults, For pregnant women

Indications

Flu, Flu and cold prevention, Herpes