Composition
Per 1 ml: Active ingredient: Oxymetazoline hydrochloride-0.5 mgm Auxiliary substances: Benzalkonium chloride-0.15 mg disodium edetate (trilon B) – 0.5 mg sodium hydroxide-up to pH 6.0-7.0 sodium dihydrogen phosphate dihydrate-1.29 mg sodium hydrophosphate dodecahydrate-1.76 mg purified water-0.1 ml
Pharmacological action
Oxymetazoline belongs to the group of alpha-adrenostimulants for topical use.
It has a vasoconstrictive effect.
When administered intranasally, it reduces swelling of the mucous membrane of the upper respiratory tract, which leads to relief of nasal breathing and opening of the mouths of the paranasal sinuses and eustachian tubes.
The effect of the drug appears 5 minutes after application and lasts for 8-12 hours.
Indications
- Treatment of acute respiratory diseases accompanied by a runny nose;
- allergic rhinitis;
- vasomotor rhinitis;
- to restore drainage in case of inflammation of the paranasal sinuses, eustachiitis, otitis media;
- to eliminate edema before diagnostic manipulations in the nasal passages.
Contraindications
The use of the drug is prohibited in some cases:
- taking monoamine oxidase inhibitors during the previous 2 weeks, within 2 weeks after their withdrawal;
- atrophic (dry) rhinitis;
- angle-closure glaucoma;
- pregnancy;
- condition after transsphenoidal pituitary surgery;
- lactation period;
- hypersensitivity to oxymetazoline and other components of the drug.
Also, Cialor ® reno should be used with caution in patients suffering from chronic renal failure, pheochromocytoma, thyroid disorders, coronary heart disease, arterial hypertension and other diseases of the cardiovascular system, diabetes mellitus, prostatic hyperplasia (urinary retention), as well as those who take bromocriptine and tricyclic antidepressants.
Side effects
Burning or dryness of the mucous membranes of the nasal cavity, dryness of the mucous membranes of the mouth and throat.
Sneezing.
An increase in the volume of secretions released from the nose (after the effect of the drug has passed).
A strong feeling of” stuffy ” nose (reactive hyperemia).
Interaction
When used concomitantly with monoamine oxidase inhibitors (including a period of 14 days after their withdrawal) and tricyclic antidepressants, an increase in blood pressure may occur. The drug slows down the absorption of local anesthetics, prolongs their effect.
How to take, course of use and dosage
Intranasally.
Adults and children over 6 years of age: apply 1-2 drops of 0.05% solution in each nasal passage 2-3 times a day.
Children from 1 year to 6 years: apply 1-2 drops of 0.025% solution in each nasal passage 2-3 times a day.
Children under 1 year of age: children under 4 weeks of age are prescribed 1 drop of 0.01% solution in each nasal passage 2-3 times a day. From the 5th week of life to 1 year-1-2 drops in each nasal passage 2-3 times a day.
It is not recommended to use the drug for more than 7 days.
With frequent and prolonged use of the drug, the feeling of “stuffy” nose may reappear or worsen.
If these symptoms occur, you should stop treatment and consult a doctor.
Overdose
Symptoms: nausea, high blood pressure, tachycardia, central nervous system depression.
Treatment: symptomatic.
Form of production
Nasal capsaics.
Active ingredient
Oxymetazoline
Dosage form
nasal drops
Description
Children’s forms
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Side effects of Sialor Rhino Renewal nasal drops 0.05% vial with nebulizer, 10ml
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