Skinoclear gel for external application 15%, 30g

Composition

100 g of cream contains the Active ingredient: azelaic acid – 20.00 g.

Pharmacological action

It causes a moderate cytostatic effect (due to inhibition of cellular protein synthesis), which is manifested in the normalization of keratinization processes in the wall of sebaceous follicles; it has an antimicrobial effect both on the skin surface and in the sebaceous glands, as well as an anti – inflammatory effect (reducing the metabolism of neutrophilic granulocytes and their production of free radical oxygen forms-important factors in maintaining the inflammatory process). With prolonged use of the drug, no resistance of microorganisms is formed. Azelaic acid dose-dependently inhibits the growth and viability of abnormal melanocytes. The therapeutic effect in hyperpigmentation (melasma) is due to inhibition of DNA synthesis and/or suppression of cellular respiration of abnormal melanocytes.

Indications

• Common acne (acne vulgaris);
• Hyperpigmentation of the melasma type, such as chloasma.

Contraindications

• Hypersensitivity to azelaic acid and other components of the drug;
• Children under 12 years of age.

How to take, course of use and dosage

Externally. The maximum duration of therapy depends on the individual picture of the disease and the severity of symptoms and is set by the attending physician. For adults and children over 12 years of age, the cream is applied evenly in a thin layer 2 times / day (morning and evening)to pre-cleansed (with mild cleansers and water) and dried areas of the face and, if necessary, neck and upper chest affected by acne. For the entire surface of the face, about 2.5 cm of the cream column is enough. The drug should be used regularly throughout the entire course of treatment, the duration of which depends on the severity of the disease. The minimum duration of treatment for melasma is 3 months. During the treatment of melasma, it is necessary to apply sunscreens (UV B and UV A) in order to prevent exacerbation of the disease and/or re-pigmentation of the skin under the influence of the sun. In patients with acne vulgaris, a marked improvement is usually observed after 4 weeks. For best results, the drug should be continued for several months.

Form of production

Cream for external use 20%.10 or 30 g in aluminum tubes. 10,15,20,25,30 or 50 g in cans of dark glass of the BTS type made of glass with stretchable lids. A self-adhesive label is applied to the jar. Each tube or jar together with the instructions for use is placed in a cardboard package (pack) made of cardboard for consumer packaging. It is allowed to complete 2 or 3 cardboard packages (bundles) in a group package (transport container) made of cardboard for consumer packaging.

Active ingredient

Azelaic Acid

Dosage form

gel for external use