Composition
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1 ml of the solution for external use contains: Â
nitric acid 70% 5807 mg,
acetic acid 99% 411 mg,
oxalic acid dihydrate 574 mg,
lactic acid 90% 45 mg,
copper nitrate (II) trihydrate 48 mcg.
Excipients: distilled water.
Pharmacological action
Solcoderm is a drug for the topical treatment of benign superficial skin lesions.
The complex effect of Solcoderm components on the affected skin area provides direct intravital fixation with subsequent mummification of pathologically altered tissue with which the drug comes into contact.
The direct effect of the drug is expressed in discoloration of the skin with the appearance of a characteristic pale gray or yellowish hue. The tissue devitalized after exposure to the drug becomes dehydrated and becomes dark brown as it becomes mummified. The resulting mummified scab spontaneously peels off after a few days or weeks.
Healing is rapid; complications in the form of secondary infection or the appearance of scar tissue are rare.
Indications
For external use in the treatment of benign skin changes:
– Common warts (Verruca vulgaris). – Plantar warts (Verruca plantaris). – Genital warts (Condylomata acuminata). – Non-cellular nevus tested for good quality (Naevus naevo-cellularis).
Use during pregnancy and lactation
Studies on the possible effect of the drug on the body of women during pregnancy and lactation have not yet been conducted. Solcoderm can be used during pregnancy and lactation only in cases where the potential benefit of its use exceeds the possible risk to the fetus or child.
Experimental studies on animals have shown that there is no risk factor for the fetus.
Contraindications
– Malignant neoplasms of the skin that are prone to metastasis (including malignant melanoma). – A pronounced tendency to form scar tissue.
Solcoderm can not be used to remove freckles and kelloid scars.
Side effects
Local reactions: short-term burning sensation within a few minutes after application of the drug; moderate transient erythema and temporary appearance of a white ischemic ring on healthy skin around the site of application of the drug (do not require special treatment); in very rare cases – changes in skin pigmentation and scar tissue formation.
Interaction
No data available.
How to take, course of use and dosage
Solcoderm is intended for external use only; the procedure should be performed by a doctor or qualified medical personnel under the supervision of a doctor.
Before the procedure, the area of the affected area of the skin is treated with ethyl alcohol or ether. Solcoderm is applied directly to the affected area of the skin. To apply the drug to the skin, a special plastic applicator with sharp and blunt ends is used, which is available in the package. The sharp edge is mainly used to apply the drug to small areas of the affected skin; the blunt end is used to treat large lesions.
As an alternative method of applying the drug, the attached glass capillary is used. Combined skin lesions with an area of 2-3 cm2 can also be treated with a glass capillary. To fill a glass capillary with the drug, it must be immersed in a Solcoderm solution for several minutes. Special care should be taken when applying, avoiding applying too large volumes of Solcoderm solution and damaging the deep layers of the fabric. It is necessary to apply as much solution as it is absorbed by the tissue of the affected area of the skin.
Solcoderm is carefully applied to the affected area of the skin with a plastic applicator or glass capillary and then distributed over the surface of the selected area of the skin with light pressure using a plastic applicator until the solution completely penetrates the tissue. During the next 3-5 minutes, it is necessary to carefully monitor the changes occurring on the treated area: skin discoloration occurs with the appearance of a characteristic pale grayish or yellowish tint. The procedure should be repeated until the above changes in skin color occur.
When treating keratinized warts, the top layer of the stratum corneum should be removed first.
Affected areas of the skin with a diameter of more than 10 mm are treated with Solcoderm only if it is established that only the upper layer of the skin is pathologically modified.
In the presence of numerous foci of skin damage, treatment with Solcoderm should be carried out in several stages, with an interval of approximately 4 weeks. During each procedure, no more than 2-3 lesions with a total area of no more than 2-3 cm2 can be treated.
Within a few days after the procedure, the treated area of the skin becomes dark brown and dries out with the formation of a scab. In case of unsatisfactory mummification of pathologically altered tissue, the procedure can be repeated in a few days.
In order to promote the fixation and mummification of pathologically altered tissues that have been treated, the affected areas should be treated 2-3 times a day with a swab moistened with 70% ethyl alcohol solution (especially after taking a bath or after washing).
Do not remove the scab by scraping or using mechanical means. The scab should disappear spontaneously, otherwise it may disrupt the healing processes of tissues and the formation of scars.
Overdose
Symptoms: the use of Solcoderm in too large doses can lead to acid burns and damage to the deep layers of the skin. Treatment: An ulcer resulting from an overdose is treated like a normal wound.
Special instructions
After a biopsy of the affected skin area, it is recommended to wait 8-10 days before starting treatment with Solcoderm solution. When treating affected areas of the skin located near the mucous membranes, including near the eyes, special precautions should be taken. If the Solcoderm solution accidentally gets on healthy skin, it should be immediately removed using a cotton swab moistened with water. If the Solcoderm solution accidentally gets into the eye, it is necessary to immediately flush the eye with a large amount of water or with a weak alkaline solution (1% sodium bicarbonate solution). Drops of Solcoderm solution that get on furniture or clothing should be washed off with water, since Solcoderm can destroy the materials from which they are made. It is not allowed to use the drug Solkoderm on inflamed areas of the skin. Special care is required in the treatment of benign skin neoplasms with Solcoderm that have previously been treated with other drugs or other methods. In case of pain at the time of application of the drug, treatment should be immediately interrupted. If there is severe local irritation and severe itching on the skin areas adjacent to the site of application of the drug, it is recommended to use a cream containing corticosteroids, or an ointment with an anesthetic effect. Before discarding the used ampoule, the remaining solution should be washed off in running water. An empty ampoule can be discarded in a garbage container. Exposure to direct sunlight and ultraviolet radiation should be avoided until complete healing of the affected area treated with Solcoderm is achieved (approximately 2-4 months after therapy). For each therapeutic procedure, it is necessary to use a new ampoule, because after opening the ampoule, the Solcoderm solution is chemically unstable. The opened ampoule should be stored strictly vertically by fixing it in a special socket of the contour packaging for ampoules. There are no restrictions on the use of Solcoderm in children over 5 years of age.
Form of production
Solution for external use.
Storage conditions
The drug should be stored at a temperature of 8° to 20°C.
Shelf
life is 2 years.
Active ingredient
Acetic acid, Nitric acid, Lactic acid, Oxalic acid, Copper nitrate
Conditions of release from pharmacies
By prescription
Dosage form
solution for external use
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Side effects of Solcoderm, 0.2ml ampoule, 1pc
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