Composition
Active ingredient:
Mebeverinee hydrochloride 200 mg;
Auxiliary substances:
colloidal silicon dioxide (aerosil),
hypromellose (hydroxypropylmethylcellulose of the Benetsel MR 874 brand),
povidone (plasdon K 90, collidone 90 F),
magnesium stearate
Pharmacological action
Antispasmodic of myotropic action, has a direct effect on the smooth muscles of the gastrointestinal tract (mainly on the large intestine).
Eliminates spasm without affecting normal intestinal motility. It does not have an anticholinergic effect.
Pharmacokinetics
When taken orally, it undergoes presystemic hydrolysis and is not detected in plasma. It is metabolized in the liver to veratric acid and Mebeverine alcohol.
It is mainly excreted by the kidneys in the form of metabolites, in small amounts – with bile. Mebeverine capsules have the property of prolonged release.
Even after repeated use, there is no significant accumulation.
Indications
Spastic states of the gastrointestinal tract caused by organic diseases.
Symptomatic treatment of pain, spastic states, unpleasant sensations in irritable bowel syndrome.
Contraindications
- hypersensitivity,
- porphyria.
Side effects
- nausea,
- allergic reactions,
- dizziness,
- headache,
- diarrhea,
- constipation.
How to take, course of use and dosage
Inside adults and children over 12 years of age: 1 capsule (200 mg) 2 times a day for 20 minutes before meals (morning and evening).
Swallow whole with water.
Special instructions
Impact on the ability to drive vehicles and engage in potentially dangerous activities.
During the treatment period, caution should be observed when driving vehicles and engaging in potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Form of production
Capsules
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C.
Shelf life
2 years
Active ingredient
Mebeverine
Conditions of release from pharmacies
By prescription
Dosage form
long-acting capsules
Description
Adults as prescribed by a doctor
Indications
From flatulence, From diarrhea, From biliary dyskinesia, From gastrointestinal spasms
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Side effects of Sparex capsules with prolonged action 200mg, 30pcs.
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