Staphylococcus bacteriophage, bottles 100ml

Composition

The drug is a phagolysate filtrate active against staphylococcal bacteria of the most common phagotypes, including Staphylococcus aureus.

Pharmacological action

Staphylococcal bacteriophage is an immunobiological preparation, phage.

The staphylococcal bacteriophage has the ability to specifically lyse staphylococcal bacteria isolated from purulent infections, including Staphylococcus aureus.

Indications

Staphylococcal bacteriophage is used for the treatment and prevention of purulent infections of the skin, mucous membranes, visceral organs caused by staphylococcal bacteria, as well as dysbiosis:

• diseases of ear, throat, nose, respiratory tract and lungs (sinusitis, otitis media, tonsillitis, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy);
• surgical infection (purulent wounds, infected burns, abscess, abscess, furuncle, carbuncle, hydradenitis, panaris, infiltrated and accelerometric staphylococcal sycosis, abscess, mastitis, bursitis, tenosynovitis, osteomyelitis);
• urogenital pathology (urethritis, cystitis, pyelonephritis, colpitis, endometritis, oophoritis);
• enteric pathology (gastroenterocolitis, cholecystitis, intestinal dysbiosis);
• generalized septic diseases;
• inflammatory diseases of the newborn (omphalitis, gastroenterocolitis, sepsis);
• other diseases of staphylococcal etiologii;
• prevention of purulent processes in vieintiane wounds (surgery of the abdominal and thoracic cavity, street and industrial injuries, etc. ); for the prevention of nosocomial infections according to epidemic indications.

Contraindications

Individual intolerance.

Side effects

Reactions to the introduction of staphylococcal bacteriophage have not been established.

When administered intradermally, there may be rapidly passing reversible redness and inflammation.

Interaction

The use of staphylococcal bacteriophage does not exclude the use of other drugs.

You can perform a combined treatment with staphylococcal bacteriophage in combination with antibiotics.

How to take, course of use and dosage

An important condition for effective phage therapy is a preliminary determination of the phage sensitivity of the pathogen (determination of sensitivity to staphylococcal bacteriophage strains isolated from the patient).

Staphylococcal bacteriophage is introduced into the focus of infection. The duration of treatment is 5-15 days. The dose and method of use depend on the nature of the focus of infection (topically in the form of irrigation, lotions and tamponade; intradermally; in the abdominal, pleural, articular cavity; in the bladder through a catheter; per os and per rectum). With a recurrent course of the disease, it is possible to conduct repeated courses of treatment.

Topically in the form of irrigation, lotions and tamponing with liquid phage in an amount of up to 200 ml, taking into account the size of the affected area, or smearing with ointment.

Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and through the mouth for 7-20 days. For purulent-inflammatory diseases of the ear, throat, nose, staphylococcal bacteriophage is administered at a dose of 2-10 ml 1-3 times a day; used for rinsing, washing, instillation, use of moistened turundum (leaving them for 1 hour).

In boils and carbuncles, liquid staphylococcal bacteriophage is introduced directly into the focus or under the base of the infiltrate, as well as around it. Injections are made daily, every other day, depending on the reaction in consistently increasing doses: for 1 injection – 0.5 ml, then 1 – 1,5 – 2 ml. In total,3-5 injections are performed during the treatment cycle.

In abscesses, staphylococcal bacteriophage is injected into the cavity of the lesion after puncture removal of pus. The amount of drug administered should be slightly less than the volume of removed pus. When opening the abscess, a swab is inserted into the cavity, abundantly moistened with staphylococcal bacteriophage.

In chronic osteomyelitis, staphylococcal bacteriophage is infused into the wound immediately after its surgical treatment. For the treatment of deep forms of pyoderma, staphylococcal bacteriophage is used intradermally in small doses of 0.1-0.5 ml in one place or, if necessary, up to 2 ml in several places. A total of 10 injections every 24 hours.

Introduction of up to 100 ml of bacteriophage into the abdominal, pleural, articular and other cavities. Capillary drainage is left, through which the bacteriophage is re-introduced every other day, only 3-4 times.

With cystitis, a staphylococcal bacteriophage is inserted into the bladder cavity using a catheter. With purulent pleurisy, bursitis or arthritis, staphylococcal bacteriophage is introduced into the cavity after removing pus from it in an amount of up to 20 ml. and more, every other day,3-4 times.

Inside in the form of tablets, staphylococcal bacteriophage is used to treat urogenital infectious pathology – cystitis, pyelitis, pyelonephritis, endometritis, salpingoophoritis, enteral infections and other diseases caused by Staphylococcus bacteria.

In intestinal forms of the disease caused by staphylococcus and intestinal dysbiosis, liquid staphylococcal bacteriophage is used: inside 3 times a day on an empty stomach 1.5-2 hours before meals; rectally-once a day (liquid in the form of enemas or candles). With intestinal dysbiosis, treatment is carried out for 7-10 days under bacteriological control. Children of the first days of life in the first two doses of staphylococcal bacteriophage are diluted with boiled water 2 times. In the absence of adverse reactions (regurgitation, skin rash), an undiluted drug is used in the future. In this case, it can be mixed with breast milk.

In sepsis, enterocolitis of newborns, including premature babies, staphylococcal bacteriophage is used in the form of high enemas (through a gas outlet tube or catheter) 2-3 times a day. A combination of rectal (enema) and oral (oral) use of the drug is possible.

In the treatment of omphalitis, pyoderma, infected wounds in newborns, staphylococcal bacteriophage is used in the form of applications twice daily (a gauze napkin is moistened with staphylococcal bacteriophage and applied to the umbilical wound or to the affected skin area).

Recommended dosage of Staphylococcal Bacteriophage:

Age of dose for 1 reception inside the liquid enema (ml. )Up to 6 months 5-10 ml 20 From 6 to 12 months 10-15 ml 20 From 1 year to 3 years 15-20 ml 40 from 3 to 8 years 20-50 ml 40-100 From 8 years and older 20-50 ml 40-100 The frequency of taking the liquid preparation is 2-3 times a day.

Staphylococcal bacteriophage is used for prophylaxis in the amount of 50 ml. for irrigation of postoperative wounds, etc.

In order to prevent sepsis and enterocolitis in newborns with intrauterine infection or the risk of nosocomial infection, staphylococcal bacteriophage is used in the form of enemas 2 times a day for 5-7 days.

Special instructions

Staphylococcal bacteriophage liquid is not suitable for use in the presence of turbidity and flakes.

Form of production

Solution

Storage conditions

Store in a dry place, protected from light, at a temperature of 2-8°C.

Shelf life

1 year

Active ingredient

Staphylococcal bacteriophage

Dosage form

solution for oral use

Description

Children as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Cholecystitis, Arthritis, Pneumonia, Boils, Otitis media, Osteoarthritis, Urethritis, Burns, Gastritis, Osteomyelitis, Pharyngitis, Intestinal infections, Dysbiosis, Tracheitis, Enteritis, Bursitis, Purulent wounds, Sore throat