Stellanin, 3% ointment, 20g

Composition

Composition in 100 g of ointment: Active ingredient:  

• 1,3-diethylbenzimidazolium triiodide – 3.0 g

Auxiliary substances:  

• povidone (polyvinylpyrrolidone low molecular weight),
• dimexide,
• glycerol( glycerol),
• vaseline

Pharmacological action

Pharmaceutical Group:

A drug with anti-inflammatory, antimicrobial and tissue regeneration-enhancing effects.

Pharmaceutical action:  

The active component of Stellanin is 1,3-diethylbenzimidazolium triiodide. The mechanism of pharmacological activity of the drug consists in the direct regenerative effect of 1,3-diethylbenzimidazolium on damaged skin. Active iodine, which is part of the preparation, inactivates bacterial wall proteins and bacterial enzyme proteins, thereby exerting a bactericidal effect.

Stellanin protects the wound surface from infections, suppresses the course of the infectious process and promotes healing. The drug has a wide spectrum of antibacterial activity.

Stellanin is susceptible to Staphylococcus aureus, Clostridium dificus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus viridans, Streptococcus haemolyticus, Proteus mirabilis, Escherichia coli, Neisseria spp. ; fungi Candida albicans and some other pathogens.

Pharmacokinetics:  

Stellanin Ointment:

Systemic absorption of the Active ingredient is absent even with damaged skin, however, therapeutic concentrations of the drug are present in the wound.

Indications

• Bedsores;
• trophic ulcers of the lower extremities;
• burns of the first and second degree;
• abrasions, cuts, scratches, cracks, scratching, including after insect bites;
• additional treatment of aseptic postoperative wounds (after excision, coagulation, episiotomy, for the treatment of skin cracks, wounds and sutures);
• acceleration of skin graft engraftment.

Contraindications

• Thyroid adenoma;
• thyrotoxicosis;
• acute renal failure;
• concomitant therapy with radioactive iodine;
• children under 18 years of age;
• I trimester of pregnancy;
• hypersensitivity to the components of the drug.

With caution. Chronic renal failure, II and III trimesters of pregnancy, lactation.

Side effects

In rare cases, allergic skin reactions (itching, hyperemia of the skin) are possible, if they occur, the drug should be discontinued.

Interaction

Do not use the drug in combination with other antiseptics containing mercury, oxidizing agents, alkalis and cationic surfactants. In the presence of blood, the bactericidal effect of the drug may decrease.

How to take, course of use and dosage

The drug is applied to the damaged skin surface so that the skin area is completely covered with the drug. The duration and frequency of application of the drug depends on the severity of the disease and the localization of the process. The daily dose should not exceed 10 g. It is possible to use occlusive dressings and patches.

In the treatment of granulating burns, wounds and trophic ulcers with weak exudation, the drug is applied in a uniform layer 1-1.5 mm thick so that the entire affected surface is covered with ointment, and a sterile gauze dressing is applied.

Bandages are changed once every 1-2 days in the treatment of burns and 1-2 times/day. in the treatment of wounds and trophic ulcers. With an open method of treating burns, the drug is applied 1-2 times/day. The duration of treatment is determined by the dynamics of wound epithelialization.

For minor skin injuries (abrasions, cuts, scratches, cracks, combs), the drug is applied in a thin layer on the affected surface 2 times a day.

Overdose

Cases of overdose are not described.

If the drug is accidentally taken orally, nausea and vomiting may occur.

It is necessary to wash the stomach and consult a doctor, if necessary, conduct symptomatic treatment.

Special instructions

The ointment should not be applied to the mucous membranes.

If the drug gets into the eyes or on the mucous membrane, it is necessary to rinse with warm water.

Form of production

Ointment.

Active ingredient

Diethylbenzimidazolium triiodide

Dosage form

ointment