Streptocid ointment, 10%, 25g

Composition

Active ingredient:

sulfonamide

Pharmacological action

Streptocide is a broad-spectrum antibacterial agent. Sulfonamide (streptocide) is one of the first representatives of the sulfonamide group of chemotherapeutic agents.

It has a bacteriostatic effect. The mechanism of action is determined by competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to a violation of the synthesis of dihydrofolic acid, and then tetrahydrofolic acid, and as a result – to a violation of the synthesis of nucleic acids.

Sulfonamide is active against gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, as well as against Chlamydia spp., Actinomyces spp., Toxoplasma gondii.

Indications

• Infected wounds of various etiologies,
• burns of I and II degrees,
• superficial pyoderma,
• boils,
• carbuncles,
• vulgar acne,
• impetigo and other purulent-inflammatory skin diseases.

Contraindications

• Hypersensitivity,
• anemia,
• renal / hepatic insufficiency,
• congenital glucose-6-phosphate dehydrogenase deficiency,
• azotemia,
• porphyria,
• pregnancy,
• lactation.

Side effects

• allergic skin reactions;
• nephrotoxic reactions (most likely in patients with impaired renal function);
• in isolated cases – hypothyroidism.

Interaction

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

How to take, course of use and dosage

Apply to the affected areas of the skin and mucous membranes. Bandages are performed in 1-2 days.

Form of production

Ointment for external use

Storage conditions

In a cool, dark place

Shelf life

5 years

Active ingredient

Sulfonamide

Dosage form

ointment