Composition
Active ingredient: Sulfonamide 2.0 g
Pharmacological action
Pharmacotherapy group: Â Antimicrobial agent – sulfonamide. ATX: D. 06. B. A Sulfonamides Pharmacodynamics : Streptocide – antimicrobial bacteriostatic agent, sulfonamide. The mechanism of action is due to competitive antagonism with paraaminobenzoic acid (PAA), inhibition of dihydropteroate synthase, and disruption of the synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidipes. Active against gram-positive and gram-negative cocci, Escherichia coli. Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis. Chlamydia spp., Actinomyces israelii. Toxoplasma gondii. When applied to the skin, it promotes rapid wound healing and erosion epithelization.
Indications
As part of complex therapy: purulent wounds, infected burns (I-II degrees) and other purulent-inflammatory processes of soft tissues.
Contraindications
-Hypersensitivity to sulfonamides;
– hepatic or renal failure;
– diseases of the hematopoietic system;
– suppression of bone marrow hematopoiesis;
– anemia;
– chronic heart failure;
– congenital glucose-6-phosphate dehydrogenase deficiency;
– azotemia;
– porphyria;
– thyrotoxicosis;
– pregnancy and lactation.
With caution:
Children’s age.
Side effects
With hypersensitivity to sulfonamide agents, allergic reactions are possible, the development of which requires immediate discontinuation of the drug. In addition, headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria are possible. If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Interaction
Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.
How to take, course of use and dosage
Externally, apply directly to the affected surface (as a powder for external use). Bandages are performed in 1-2 days. Maximum doses for adults: single dose – 5 g, daily dose – 15 g. Children over 3 years of age – 300 mg-a single dose, a daily dose of 300 mg.
Overdose
Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual disturbances, fever, hematuria, crystalluria; with prolonged overdose – thrombocytopenia, leukopenia, megaloblastic anemia, jaundice. Treatment: heavy drinking; in case of accidental ingestion-gastric lavage.
Special instructions
During therapy, a plentiful alkaline drink is recommended. If necessary, antimicrobial drugs are prescribed inside. Influence on the ability to drive vehicles and mechanisms: Taking into account the side effects of the drug, care should be taken when driving vehicles and mechanisms.
Storage conditions
Store in a dry place protected from light at a temperature not exceeding 25 °C. Keep out of reach of children.
Shelf
life is 5 years.
Active Ingredient
Sulfonamide
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Side effects of Streptocide powder, 2g.
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