Streptocide, soluble liniment 5% 30g

Composition

>of 1 g of liniment contains: Active ingredient: Sodium sulfonamide (soluble streptocide) — 0.05 g (in terms of 100% substance); Excipients: Glycerol (distilled glycerin) – 0.30 g, Emulsifier No. 1 (Lanette® SX) – 0.080 g, Water (purified water) – up to 1 g

Pharmacological action

Streptocide is a broad-spectrum antibacterial agent. Sulfonamide (streptocide) is one of the first representatives of the sulfonamide group of chemotherapeutic agents.

It has a bacteriostatic effect. The mechanism of action is determined by competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase.

This leads to a violation of the synthesis of dihydrofolic acid, and then tetrahydrofolic acid, and as a result – to a violation of the synthesis of nucleic acids.

Sulfonamide is active against gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, as well as against Chlamydia spp., Actinomyces spp., Toxoplasma gondii.

Active Ingredients

Sulfonamide

Indications

• infected wounds of various etiologies,
• burns of I and II degrees,
• superficial pyoderma,
• boils,
• carbuncles,
• vulgar acne,
• impetigo and other purulent-inflammatory skin diseases.

Contraindications

Hypersensitivity to the components of the drug, anemia, renal / hepatic insufficiency, congenital glucose-6-phosphate dehydrogenase deficiency, azotemia, porphyria, pregnancy, lactation. With caution, children under 3 months of age.

Side effects

From the digestive system:  nausea, vomiting, diarrhea.

From the hematopoietic system:  rarely – eosinophilia, thrombocytopenia, leukopenia, hypoprothrombinemia, agranulocytosis.

From the central nervous system and peripheral nervous system:  in isolated cases – visual impairment, headache, dizziness, peripheral neuropathy, ataxia.

Other services:  allergic skin reactions; rarely-nephrotoxic reactions (most likely in patients with impaired renal function); in isolated cases-hypothyroidism.

Interaction

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

How to take, course of use and dosage

Externally. Liniment is applied to a gauze bandage, which is applied to the affected area; bandages are made after 1-2 days. With a large lesion area, the daily dose of liniment in terms of sulfonamide should not exceed 6 g in adults (corresponds to 120 g of liniment),0.6 g in children under 1 year (corresponds to 12 g of liniment),1.8 g in children 1-5 years (corresponds to 36 g of liniment),0.5 g in children 5-12 years (corresponds to 60 g of liniment).

Overdose

Symptoms:  

nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual disturbances, fever, hematuria, crystalluria; with prolonged overdose – thrombocytopenia, leukopenia, megaloblastic anemia, jaundice.

Treatment:  

copious drinking; in case of accidental ingestion of ointment and powder inside-gastric lavage.

Description

Antimicrobial agent — sulfonamide

Description

White or creamy white liniment color, with a specific smell.

Complete set

Liniment 5%.30 g each in aluminum tubes or polyethylene laminate tubes. Each tube together with the instructions for medical use of the drug is placed in a pack of cardboard.

Special instructions

In the treatment of extensive skin lesions, a rich alkaline drink is recommended. Influence on the ability to drive vehicles and work with mechanisms The drug does not affect the ability to drive vehicles and engage in potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Ointment (liniment) for external use.

Storage conditions

At a temperature not exceeding 25 C. Keep out of reach of children!

Shelf

life is 4 years. Do not use the product after the expiration date indicated on the package.

Active ingredient

Sulfonamide

Dosage form

ointment

Description

For adults

Indications

Burns, Purulent Wounds, Bedsores, Pyoderma, Skin Infections