ATC code | B01AA03 |
---|---|
CAS Number | 9002-04-4 |
Other product names | Streptase, Kabikinase, Streptokinase Karma |
Dosage form | Lyophilized powder for solution for intravenous and intraarterial injection |
Active ingredient | Streptokinase |
Other ingredients | Polygeline, sodium glutamate monohydrate |
Pharmacological classification | Fibrinolytic agent |
Pharmacological action | Activation of plasminogen, fibrinolysis, thrombolysis |
Storage conditions | Store in a refrigerator (2-8°C) |
Streptokinase 1500000ME: What is it?
Streptokinase 1500000ME is a thrombolytic agent used to dissolve blood clots in various areas of the body. It helps restore normal blood flow by breaking down existing clots. It is commonly used in cases of acute myocardial infarction (heart attack).
Uses of Streptokinase 1500000ME
- Lung blood clot (pulmonary embolism)
- Deep vein thrombosis (leg blood clot)
- Blood clot in the arteries (arterial thrombosis)
Structure of Streptokinase 1500000ME
Produced by group C beta-hemolytic streptococci, Streptokinase 1500000ME is a pure preparation of a bacterial protein. It is lyophilized (freeze-dried) and then reconstituted before injection. Each vial contains 1.5 million International Units (IU) of streptokinase.
How Streptokinase 1500000ME Works
Streptokinase 1500000ME works by activating plasminogen, a protein found in the blood. This activation leads to the production of plasmin, an enzyme that breaks down fibrin, the protein responsible for forming blood clots. By dissolving the clot, Streptokinase 1500000ME helps restore normal blood flow and prevent further complications.
Specific Uses of Streptokinase 1500000ME
- Pulmonary Embolism: Lung blood clots can be life-threatening. Streptokinase 1500000ME can help dissolve these clots, improving breathing and overall well-being.
- Deep Vein Thrombosis: Deep vein thrombosis can cause pain, swelling, and even pulmonary embolism. Streptokinase 1500000ME can dissolve these clots, reducing the risk of complications.
- Arterial Thrombosis: Arterial blood clots can restrict blood flow to vital organs. Streptokinase 1500000ME can break down these clots and improve blood flow.
How to Use Streptokinase 1500000ME
Streptokinase 1500000ME is typically administered by a healthcare professional through an intravenous (IV) injection. The dosage and duration of treatment depend on the individuals condition, the severity of the clot, and other factors. It is crucial to follow the doctors instructions precisely and complete the prescribed course of treatment.
Dose and Administration of Streptokinase 1500000ME
Your doctor will determine the appropriate dosage of Streptokinase 1500000ME based on your specific needs. It is usually given as a bolus injection followed by a continuous infusion. The specific dosage and duration of treatment, as well as the patients response, will vary depending on the condition being treated. Consult your doctor for personalized advice on the appropriate dosage and administration for your specific situation.
Side Effects of Streptokinase 1500000ME
Like all medications, Streptokinase 1500000ME can have side effects. The most common side effects include:
- Bleeding: Gastrointestinal bleeding, nosebleeds, and bruising
- Fever
- Allergic reactions: Rash, itching, swelling
- Acute headache
- Nausea
- Muscle soreness
Rarely, more serious side effects may occur, including:
- Stroke
- Internal bleeding
- Anaphylaxis: A severe allergic reaction
If you experience any side effects, especially severe ones, inform your doctor immediately.
Contraindications of Streptokinase 1500000ME
Not everyone is suitable for Streptokinase 1500000ME. Patients with the following conditions should not use it:
- Active or recent internal bleeding
- Brain tumor
- Allergy to streptokinase or any component
- Recent intracranial or intraspinal surgery
- Uncontrolled blood pressure
- Current head trauma
- Acute pancreatitis
- Recent head injury
- Hemorrhagic conditions
- Severe liver or kidney disease
- Brain blood vessel diseases
- Recent surgery
- Uncontrolled hypertension
- Lung problems
Before taking Streptokinase 1500000ME, inform your doctor about any allergies or pre-existing medical conditions. They can assess your individual risks and determine if this medication is appropriate for you.
Other Important Information about Streptokinase 1500000ME
Streptokinase 1500000ME is a potent medication and should only be used under the supervision of a licensed medical professional. It is crucial to follow your doctors instructions precisely and report any side effects immediately.
This information is for general knowledge and should not be considered a substitute for professional medical advice. Always consult your doctor or another qualified healthcare provider for personalized medical advice and treatment recommendations.
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Side effects of Streptokinase 1500000IU
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