Structum, capsules 0.5g, 60pcs

Composition

1 capsule contains:

Active ingredient: Chondroitin sodium sulfate 500 mgm Auxiliary substances: Talcum powder 10 mgcomposition of capsule shells (casings and caps): indigo carmine, titanium dioxide, gelatin

Pharmacological action

Structum affects the metabolic processes in hyaline and fibrous cartilage, reduces degenerative processes in the cartilage tissue of joints, and stimulates the biosynthesis of glycosaminoglycans. Slows down bone resorption and reduces calcium loss, accelerates the processes of bone recovery. When using the drug Structum reduces soreness and improves the mobility of the affected joints. The therapeutic effect persists for a long time after the end of the course of therapy.

Pharmacokinetics

Suction and distribution

After oral use, more than 70% of chondroitin sulfate is absorbed from the gastrointestinal tract. After a single dose at an average therapeutic dose, Cmax in blood plasma is reached in 3-4 hours, in synovial fluid – in 4-5 hours. Bioavailability of the drug is 13%. Chondroitin sulfate accumulates in the synovial fluid.

Deduction

It is excreted by the kidneys.

Indications

• osteoporosis
• fractures (to accelerate the formation of callus)
• osteoarthritis.

Use during pregnancy and lactation

It is not recommended due to the lack of sufficient clinical data.

Contraindications

Pregnancy; lactation (breastfeeding).

Side effects

Rarely:  allergic reactions, nausea, diarrhea.

Interaction

Concomitant use of Structum may increase the effect of indirect anticoagulants, antiplatelet agents and fibrinolytics.

How to take, course of use and dosage

Inside, washed down with water.

Adults and adolescents from 15 years of age — 1 g / day: 2 capsules (250 mg) or 1 capsule (500 mg) 2 times a day.

The recommended duration of the initial course is 6 months, the period of action of the drug after its withdrawal is 3-5 months, depending on the localization and stage of the disease, the duration of repeated courses is set by the doctor.

Special instructions

With caution, prescribe the drug for bleeding or a tendency to bleed.

Form of production

Capsules

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Chondroitin sulfate

Dosage form

Capsules