Composition
1 tablet contains:
iron sulfate II polutornovodny 256.3 mg (corresponds to 80 mg of iron).
Auxiliary substances:
mucoproteose,
ascorbic acid,
potato starch,
eudragite C,
dibutyl fatalate,
povidone,
magnesium stearate,
castor oil,
magnesium trisilicate.
Shell composition:
talc, eudragite E, titanium dioxide, starch, wax, paraffin, sucrose.
Pharmacological action
Tardiferon retard makes up for iron deficiency in the body, which is necessary for the synthesis of hemoglobin.
Mucoproteose, a mucopolysaccharide obtained from the intestinal mucosa, provides better tolerability of the drug and increases bioavailability and gradual release of divalent iron (Fe2+) from the drug.
Ascorbic acid helps improve iron absorption. After taking the drug, iron absorption occurs mainly in the distal part of the small intestine. The maximum concentration of iron ion in the blood plasma is reached 7 hours after taking the drug and remains elevated during the day.
On average,10-20% of the dose is absorbed. Absorption increases with a decrease in iron reserves in the body.
Indications
Treatment and prevention of iron deficiency conditions caused by: – Pregnancy. – Lactation. – Malabsorption of iron from the gastrointestinal tract. – Prolonged bleeding. – Poor and unbalanced nutrition.
Use during pregnancy and lactation
Pregnant women (II and III trimester of pregnancy) and lactating women are recommended to take 1 tablet every other day for preventive purposes.
Contraindications
-Hypersensitivity to the components of the drug.
– Diseases associated with the accumulation of iron in the body: aplastic anemia, hemolytic anemia, thalassemia, hemosiderosis, hemochromatosis. – Violation of iron absorption: sideroachrestic anemia, lead anemia, pernicious anemia (vitamin B12 deficiency), children’s age (up to 6 years).
Interaction
When taking Tardiferon simultaneously with antacids, tetracycline antibiotics and penicillamine, iron absorption worsens.
When taking ascorbic acid at the same time, iron absorption improves. It should not be administered together with other iron preparations, including for parenteral use, in order to avoid overdose.
How to take, course of use and dosage
The drug is taken orally after a meal.
The duration of therapy is determined by the doctor individually.
Adults – 1-2 tablets per day.
Pregnant women (II and III trimester of pregnancy) and lactating women are recommended to take 1 tablet every other day for preventive purposes.
Overdose
Symptoms: nausea, vomiting, diarrhea.
Treatment: if an overdose is suspected, it is necessary to conduct a study of the serum iron content and serum ferritin level, perform gastric lavage, prescribe milk and raw egg inside to strengthen the binding of iron ions in the gastrointestinal tract and their subsequent excretion.
In case of significant excess of normal serum ferritin values, an iron chelator (desferal) should be prescribed.
Special instructions
Before starting iron therapy, it is necessary to conduct a study of the level of serum iron, serum ferritin (i. e., document iron deficiency).
Therapy with the drug should be carried out until the blood picture normalizes (8-12 weeks). When taking the drug, there may be a dark staining of feces, a false positive benzidine test.
It should be borne in mind that drinking tea in large quantities reduces the absorption of iron ions in the gastrointestinal tract. Special studies on the use of the drug in children have not been conducted.
Form of production
Tablets
Storage conditions
Store at a temperature not exceeding 25°C.
Shelf
life is 5 years.
Active ingredient
Iron sulfate
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
Adults, Nursing mothers, Children over 6 years of age, Children prescribed by a doctor, Pregnant women prescribed by a doctor
Indications
Anemia
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