Composition
Active ingredient:
thymogen (glutamyl-tryptophan) 100 mcg;
excipients:
sodium chloride,
water for injection
Pharmacological action
Thymogen is an immunostimulating agent, a dipeptide.
It has an immunomodulatory, anti-inflammatory, desensitizing, antioxidant, and reparative effect. It interacts with T-lymphocytes, Langerhans cells (macrophages) and mast cells of the skin, contributing to the normalization of their functional activity and intercellular interactions.
It reduces the antigen/IgE-mediated production of inflammatory mediators, pro-inflammatory cytokines and biogenic amines (histamine and serotonin) in skin cells. Causes a decrease in skin manifestations of allergic reactions with hypersensitivity to various allergens. Suppresses the inflammatory response in response to skin irritants in contact dermatitis. Reduces skin inflammation and itching of allergic dermatitis in the acute phase of the disease.
It inhibits the processes of free radical oxidation in pathologically altered skin cells, preventing their damage and death, and stimulates the production of antioxidant cell protection factors.
It stimulates the proliferation of keratinocytes, fibroblasts and endothelial cells, promoting the regeneration of damaged skin areas. Accelerates wound healing, stimulates cellular and humoral (tissue) protection factors.
Systemic effects are insignificant due to limited absorption through the skin
Indications
- Complex therapy of acute and chronic infectious and inflammatory diseases accompanied by a decrease in cellular immunity.
- Prevention of infectious complications, immune suppression, hematopoiesis, regeneration processes in the post-traumatic and postoperative period, during radiation therapy or chemotherapy, with the use of massive doses of antibiotics.
- Prevention and complex therapy of viral and bacterial infections, acute and chronic respiratory diseases.
Contraindications
Individual drug intolerance, pregnancy, breast-feeding.
Side effects
Allergic reactions.
Interaction
Increases the effectiveness of other types of therapy (cytostatics, radiation therapy, etc. );
it is not recommended to use simultaneously with large doses of corticosteroid drugs.
How to take, course of use and dosage
The solution is administered intramuscularly 1 time a day for adults at 100 mcg (300-1000 mcg per course);
children under 1 year-10 mcg, from 1 year to 3 years-10-20 mcg, from 4 to 6 years-20-30 mcg, from 7 to 14 years-50 mcg.
The duration of the course of treatment is 3-10 days, depending on the severity of immune disorders.
A second course of treatment is possible in 1-6 months.
Form of production
Solution for intramuscular use
Storage conditions
At a temperature of 2 to 10 °C.
Shelf
life is 3 years.
Active ingredient
Alpha-Glutamyl-Tryptophan
Conditions of release from pharmacies
By prescription
Dosage form
solution for injection
Description
For adults as prescribed by a doctor, for children as prescribed by a doctor
Indications
Immunodeficiency conditions, After a course of antibiotic therapy, Colds, Respiratory tract infections
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Side effects of Thymogen, ampoules 0.01%, 1ml, 10pcs.
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