Thymogen, ampoules 0.01%, 1ml, 5pcs

Composition

Active ingredient:

thymogen (glutamyl-tryptophan) 100 mcg;

Auxiliary substances:

Sodium chloride,

water for injection

Pharmacological action

Thymogen is an immunostimulating agent, a dipeptide.

It has an immunomodulatory, anti-inflammatory, desensitizing, antioxidant, and reparative effect. It interacts with T-lymphocytes, Langerhans cells (macrophages) and mast cells of the skin, contributing to the normalization of their functional activity and intercellular interactions.

It reduces the antigen/IgE-mediated production of inflammatory mediators, pro-inflammatory cytokines and biogenic amines (histamine and serotonin) in skin cells. Causes a decrease in skin manifestations of allergic reactions with hypersensitivity to various allergens. Suppresses the inflammatory response in response to skin irritants in contact dermatitis. Reduces skin inflammation and itching of allergic dermatitis in the acute phase of the disease.

It inhibits the processes of free radical oxidation in pathologically altered skin cells, preventing their damage and death, and stimulates the production of antioxidant cell protection factors.

It stimulates the proliferation of keratinocytes, fibroblasts and endothelial cells, promoting the regeneration of damaged skin areas. Accelerates wound healing, stimulates cellular and humoral (tissue) protection factors.

Systemic effects are insignificant due to limited absorption through the skin

Indications

• Complex therapy of acute and chronic infectious and inflammatory diseases accompanied by a decrease in cellular immunity;
• Prevention of infectious complications, immune suppression, hematopoiesis, regeneration processes in the post-traumatic and postoperative period, during radiation therapy or chemotherapy, when using massive doses of antibiotics;
• Prevention and complex therapy of viral and bacterial infections, acute and chronic respiratory diseases.

Contraindications

Individual drug intolerance, pregnancy, breast-feeding.

Side effects

Allergic reactions.

Interaction

Increases the effectiveness of other types of therapy (cytostatics, radiation therapy, etc. ); it is not recommended to use simultaneously with large doses of corticosteroid drugs.

How to take, course of use and dosage

The solution is administered intramuscularly 1 time a day for adults at 100 mcg (300-1000 mcg per course); children under 1 year-10 mcg, from 1 year to 3 years-10-20 mcg, from 4 to 6 years-20-30 mcg, from 7 to 14 years-50 mcg. The duration of treatment is 3-10 days depending on the severity of immune disorders. A second course of treatment is possible in 1-6 months.

Special instructions

The results of the performed clinical studies show that Thymogen in the cream dosage form meets the requirements for external therapy in the treatment of chronic dermatoses (atopic dermatitis, strofulus, microbial eczema and pyoderma) in children.

The drug suppresses inflammation in the focus, reducing puffiness and hyperemia of the skin, reduces itching, helps to quickly restore the integrity of the skin and eliminates its dryness, thereby improving the barrier function of the skin.

In addition, having an immunocorrecting effect, Thymogen increases the protective function of the skin.

Product form

solution for intramuscular use

Storage conditions

In a dark place, at a temperature not exceeding 4 °C

Shelf life

2 years

Active ingredient

Alpha-Glutamyl-Tryptophan

Conditions of release from pharmacies

By prescription

Dosage form

solution for injection

Description

For children as prescribed by a doctor, For adults as prescribed by a doctor, For children from birth

Indications

Pyoderma, Hepatitis, and Bronchitis