Composition
In one dose (0.1 ml) of the drug Active ingredient: alpha-glutamyl-tryptophan (Thymogen sodium in terms of thymogen) 25 mcg. Auxiliary substances: sodium chloride 900 mcg, benzalkonium chloride 10 mcg, purified water up to 0.1 ml
Pharmacological action
Pharmacotherapy group: Immunostimulating agent. ATX code: L03AXPharmacological properties: Pharmacodynamics : It has a regulating effect on the reactions of cellular and humoral immunity and nonspecific resistance of the body. Stimulates regeneration processes in case of their suppression. Improves the course of cellular metabolism processes. Increases the expression of differentiation receptors on lymphocytes, normalizes the number of T-helper cells, cytotoxic T-lymphocytes and their ratio in patients with various immunodeficiency conditions. Pharmacokinetics: The drug quickly enters the systemic circulation after its intranasal use. Alpha-glutamyl-tryptophan sodium under the influence of peptidases is broken down into L-glutamic acid and L-tryptophan, which are involved in peptide synthesis in the body.
Indications
- Prevention and complex therapy of acute and chronic viral and bacterial diseases of the upper respiratory tract.
- Prevention of immune suppression, hematopoiesis, and regeneration processes in the post-traumatic and postoperative periods.
- Complex adjuvant therapy to correct secondary immunodeficiency during radiation therapy, chemotherapy, and antibiotic therapy.
- Complex therapy of acute and chronic infectious and inflammatory diseases accompanied by a decrease in immunity.
If necessary, please consult your doctor before taking this medicine.
Use during pregnancy and lactation
Due to insufficient clinical data, taking the drug during pregnancy and lactation is possible only as prescribed by a doctor, if the intended benefit to the mother exceeds the potential risk to the fetus or child. Please consult your doctor before taking this medicine.
Contraindications
Hypersensitivity to the components of the drug, children under 1 year of age. If necessary, please consult your doctor before taking this medicine.
Side effects
Allergic rhinitis.
Consult your doctor if you experience the mentioned side effect or other side effects that are not listed in the instructions.
Interaction
Increases the effectiveness of chemotherapeutic drugs (cytostatic, antibacterial drugs) and radiation therapy. It is not recommended to use concomitantly with large doses of glucocorticosteroid medications. The immunosuppressive effect of high doses of these drugs eliminates the immunostimulating effect of alpha-glutamyl-tryptophan.
How to take, course of use and dosage
Locally. Hold the bottle by the base with your thumb and the dispenser nozzle between your middle and index fingers. Insert the nozzle of the metering device into the nasal passage in the vertical up position. Press the nozzle once. The drug is administered intranasally (in the nose) in doses of: Adults: 1 dose (one injection) in each nasal passage 2 times a day for 10 days for therapeutic purposes or for 3-5 days for preventive purposes. Children: from 1 year to 6 years,1 dose in one nasal passage 1 time a day, from 7 to 14 years,1 dose in each nasal passage 1 time a day. The drug is used for 10 days for therapeutic purposes or for 3-5 days for preventive purposes. A second course of Thymogen is carried out no earlier than in 1 month. Take the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before taking this medicine.
Overdose
In case of overdose, there is an abundant secretion of the nasal mucosa, which stops after the drug is discontinued. No treatment is required. In case of accidental ingestion of the drug, it is necessary to flush the stomach with water and immediately consult a doctor.
Special instructions
The drug does not have any special effects when taken for the first time and when it is canceled. There are no specific features of the use of the drug by children and adults with chronic diseases. Information about the possible effect of a medicinal product for medical use on the ability to drive vehicles and mechanisms: The drug does not adversely affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Form of production
Nasal spray dosed 25 mcg / dose of 10 ml in a dark glass bottle or polymer bottle. A dispenser pump (100 µl) with a plastic housing, nozzle and protective cap is installed in the bottle. One bottle together with the instructions for use in a pack of cardboard. The number of doses in the bottle is not less than 80.
Storage conditions
Store at a temperature of 2 ° C to 8 ° C. Keep out of reach of children.
Shelf
life is 2 years and 6 months. Do not use after the expiration date indicated on the package.
Active ingredient
Alpha-Glutamyl-Tryptophan
Dosage form
nasal spray
Description
For adults as prescribed by a doctor, for children as prescribed by a doctor
Indications
Cold, Runny nose, Flu, Respiratory tract infections, Immunodeficiency, Flu and cold prevention, After a course of antibiotic therapy
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Side effects of Thymogen, spray 250 µg/ml, 10ml
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