Composition
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of 100 g of gel for external use contains:
Active ingredient: troxerutin – 2.0 g;
excipients: carbomer-0.6 g, trollamine-0.7 g, disodium edetate-0.05 g, benzalkonium chloride, solution-0.2 g, water-96.45 g
Pharmacological action
Pharmacotherapy group
Venotonizing and venoprotective agent
ATX Code: C05CA
Pharmacodynamics :
Troxerutin-a flavonoid (a rutin derivative) has P-vitamin activity; it has a venotonizing venoprotective anti-edematous antioxidant and anti-inflammatory effect. Participates in redox processes blocks hyaluronidase stabilizes the hyaluronic acid of cell membranes and reduces the permeability and fragility of capillaries increases their tone.
Increases the density of the vascular wall reduces exudation of the liquid part of the plasma and diapedesis of blood cells.
Reduces inflammation in the vascular wall by limiting the adhesion of platelets to its surface.
Non-toxic has a wide range of therapeutic effects.
Pharmacokinetics:
When the gel is applied to the skin, the Active ingredient quickly penetrates through the epidermis in 30 minutes it is found in the dermis and in 2-5 hours in subcutaneous adipose tissue.
Indications
-Pain and edema associated with chronic venous insufficiency;
– feeling of heaviness and pain in the legs swelling of the ankles;
– fatigue swelling convulsions of paresthesia;
– acute superficial thrombophlebitis and periflebitis;
– varicose dermatitis;
– pain and edema of a traumatic nature (including when. ligament damage sprains or muscle bruises).
Use during pregnancy and lactation
There are no data on adverse effects on the fetus and newborns. The drug can be used in the second and third trimester of pregnancy, as well as during breastfeeding.
Contraindications
Hypersensitivity” to troxerutin or any auxiliary substance of the drug pregnancy (I trimester).
Violation of the integrity of the skin.
Side effects
In rare cases, there is redness, itching, and a rash. These symptoms go away quickly after treatment is stopped.
Interaction
When applied topically, Troxerutin DS are not known.
How to take, course of use and dosage
The gel is applied externally.
The gel is applied morning and evening to the affected area with light massaging movements from the bottom up until it is completely absorbed into the skin.
If for any reason the use of the drug is missed, the patient can apply it at any time, observing the interval between two treatment sessions of at least 10-12 hours.
If necessary, the gel can be applied under bandages or elastic stockings.
The course of treatment is from 2 weeks to 1-2 months.
If the disease recurs, the course of treatment can be repeated 2-3 times a year.
Overdose
There is no risk of overdose because the drug is applied externally.
If you accidentally swallow a large amount of gel, resort to washing the mouth and stomach; if necessary, prescribe symptomatic treatment.
Special instructions
Avoid contact with the gel on open wounds mucous membranes of the eye!
Patients with chronic venous insufficiency are recommended to use both in the initial and late stages of the disease.
In conditions characterized by increased vascular permeability (including scarlet fever, measles flu, allergic reactions), it is used in combination with ascorbic acid to enhance its effect.
Form of production
Gel for external use 2%.
Storage conditions
At a temperature not exceeding 25 °C.
Keep out of reach of children.
Shelf
life is 5 years.
Do not use after the expiration date.
Active ingredient
Troxerutin
Dosage form
gel for external use
Description
Pregnant women in the second and third trimester as prescribed by a doctor, For adults
Indications
Swelling after injuries and operations, Varicose veins
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Side effects of Troxerutin DS gel 2%, 45g.
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