Composition
1 capsule contains:
Active ingredient:
troxerutin 300 mg;
excipients:
lactose monohydrate-5 mg;
colloidal silicon dioxide-8 mg;
macrogol
6000-15 mg; magnesium stearate-7 mg;
shell:
gelatin; titanium dioxide — 2%; quinoline yellow dye-0.75%; sunset yellow dye-0.0059%; gelatin-up to 100%
Pharmacological action
Troxerutin Vramed has venotonizing, angioprotective, anti-inflammatory, decongestant, and antioxidant effects. Flanovoid (a rutin derivative), has P-vitamin activity; has venotonizing, angioprotective, anti-inflammatory and anti-edematous effects. Its pharmacodipamic properties are associated with the involvement of troxerutin bioflavonoids in redox processes and hyaluronidase inhibition.
By inhibiting hyaluronidase, troxerutin stabilizes the hyaluronic acid of cell membranes and reduces the permeability and fragility of capillaries, increases their tone.
It has antioxidant activity, as a result of which it prevents the oxidation of ascorbic acid, epinephrine and lipids. Prevents damage to the basement membrane of endothelial cells when exposed to various factors.
Troxerutin reduces exudative inflammation in the vascular wall by limiting platelet adhesion to its surface. As a result of treatment with troxerutin, the feeling of heaviness in the legs disappears, tissue swelling decreases, and trophic function improves.
Indications
- Chronic venous insufficiency with such manifestations as static heaviness in the legs, leg ulcers, trophic lesions of the skin;
- varicose veins, superficial thrombophlebitis, periflebit, phlebothrombosis, varicose eczema, post-thrombotic syndrome, hemorrhoids, post-traumatic swelling and hematoma, hemorrhagic diathesis with increased capillary permeability, capillariasis (i. e. measles, scarlet fever, influenza), diabetic microangiopathy, retinopathy, vascular side effects of radiation therapy;
- as a prophylactic agent after vein surgery.
Use during pregnancy and lactation
Contraindicated in the first trimester of pregnancy and breast-feeding, in the second and third trimesters of pregnancy can only be used as prescribed by a doctor.
Contraindications
Hypersensitivity, peptic ulcer of the stomach and duodenum, chronic gastritis (in the acute phase).
Side effects
Allergic reactions (skin rash), erosive and ulcerative lesions of the gastrointestinal tract, headache.
How to take, course of use and dosage
Troxerutin Vramed is taken orally, with meals,1 capsule 2-3 times a day.
For maintenance treatment — 1 capsule per day for 3-4 weeks.
Form of production
Capsules
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C
Shelf life
5 years
Active ingredient
Troxerutin
Dosage form
Capsules
Description
For adults, Pregnant women in the second and third trimester as prescribed by a doctor
Indications
Varicose veins, Vascular lesions in diabetes mellitus, Edema after injuries and operations, Vascular eye diseases, Hemorrhoids, Thrombophlebitis
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Side effects of Troxerutin Vramed, capsules 300mg, 50pcs.
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