Venoplant retard pills, 20pcs

Composition

1 tablet of prolonged action, film-coated, contains:

Active ingredient:  

horse chestnut seed extract dry (4.5-5.5: 1) (standardized by the sum of triterpene glycosides in terms of escin anhydrous-50 mg) 263.2 mg;

excipients:

core:

calcium hydrophosphate anhydrous-36.8 mg;

colloidal silicon dioxide-15.4 mg;

crospovidone-10 mg;

magnesium stearate-2 mg;

Eudragit RL 30 D — 14 mg;

Eudragitol

30 D-10 mg; povidone K

25-20 mg; polysorbate 80-0.036 mg;

triethyl citrate-3.564 mg,

 film shell:

vanilla — 0,405 mg; hypromellose — of 11.33 mg; iron oxide red (E 172) — 0,22 mg; iron oxide yellow (E 172) to 1.09 mg; macrogol 4000 of 5.67 mg; sodium saccharin — 0.025 mg; titanium dioxide (E 171) — 0,68 mg; penogasashchuu emulsion — 0.01 mg; talc — 1 mg; titanium dioxide — to 0.68 µg

Pharmacological action

Pharmacodynamics

Venoplant reduces capillary permeability, has a venotonic, anti-edematous, anti-inflammatory and angioprotective effect.

Prevents the activation of lysosomal enzymes that break down proteoglycan, increases the tone of the venous wall, eliminates venous congestion, reduces capillary permeability and fragility.

Reduces exudation, reduces fluid effusion in the tissue and accelerates the resorption of existing edema.

It slows down the processes of inflammation, improves microcirculation, and promotes the repair of organs and tissues.

Pharmacokinetics

Horse chestnut seed extract dry contains a large amount of biologically active substances, which together determine its pharmacological activity. Therefore, data on the pharmacokinetics of individual chemical components that make up the extract are insufficient for extrapolation to the drug as a whole.

Indications

Chronic venous insufficiency of class I–III according to CEAR classification:

• varicose veins,
• swelling,
• cramps in the calf muscles,
• feeling of heaviness in the legs.

Contraindications

Hypersensitivity to horse chestnut seed extract or any of the components of Venoplant; children (under 18 years of age).

Side effects

Allergic reactions: feeling hot, hives, skin rash, pruritus, anaphylactic shock, dyspepsia (including nausea), dizziness, headache.

If any adverse events occur, you should inform your doctor about them.

Interaction

Concomitant use with indirect anticoagulants is not recommended, as Venoplant enhances their effect.

How to take, course of use and dosage

Inside, before eating, without chewing, with a small amount of liquid.

1 tablet each  Venoplant 2 times a day (morning and evening); the duration of treatment is determined by the severity of the symptoms of the disease and is no more than 16 weeks.

Overdose

No overdose cases have been reported so far.

Treatment: in case of overdose, consult your doctor.

Special instructions

It is necessary to strictly follow all additional prescriptions of the doctor — bandaging the legs, wearing elastic stockings, cold foot baths. All regulations must be strictly observed.

If severe symptoms suddenly appear (especially on one leg), such as severe swelling, discoloration of the skin, a feeling of tension, heat, or pain, you should immediately consult a doctor, as they can be symptoms of a serious disease — venous thrombosis of the lower extremities.

Influence on the ability to drive vehicles and work with mechanisms. During the period of use of the drug, care should be taken when performing potentially dangerous activities that require increased attention and speed of psychomotor reactions.

Form of production

Film-coated long-acting tablets

Storage conditions

At a temperature of 15-25 °C

Shelf life

3 years

Active ingredient

Horse chestnut seed extra.

Dosage form

long-acting tablets

Description

For adults

Indications

Varicose Veins