Vicks Active Sinex nasal spray 0.05% Aloe Vera, 15ml

Composition

>of 100 ml of the solution contains:  Active substance:  

• oxymetazoline hydrochloride 0.05 g

Auxiliary substances:

• sorbitol (70% aqueous solution) 5.0 g
• sodium citrate dihydrate 0,875 g,
• tyloxapol 0.7 g,
• chlorhexidine digluconate (20% solution) of 0.27 g,
• citric acid, anhydrous 0.2 g,
• aloe Vera 0.1 g of
• benzalkonium chloride (50% solution) 0.04 g,
• levomenthol 0.015 g,
• potassium Acesulfame 0.015 g,
• cineole 0.013 g,
• L-carvone 0.01 g
• of disodium edetate 0.01 g
• of sodium hydroxide (0.1 M solution) to pH 5.4,
• distilled water to 100 ml.

Pharmacological action

Oxymetazoline belongs to the group of alpha-adrenostimulants for topical use. It has a vasoconstrictive effect. When administered intranasally, it reduces swelling of the mucous membrane of the upper respiratory tract, which leads to relief of nasal breathing and opening of the mouths of the paranasal sinuses and eustachian tubes. The effect of the drug appears 5 minutes after application and lasts for 8-12 hours. Pharmacokinetics: When applied topically, oxymetazoline is practically not absorbed.

Indications

To facilitate nasal breathing in “cold” diseases or viral infections of the upper respiratory tract, sinusitis, rhinitis of any etiology.

Contraindications

• Hypersensitivity to the components of the drug;
• atrophic (dry) rhinitis;
• taking monoamine oxidase (MAO) inhibitors during the previous 2 weeks and within 2 weeks after their withdrawal;
• angle-closure glaucoma;
• condition after transsphenoidal pituitary surgery;
• children under 6 years of age;
• pregnancy;
• lactation.

The drug should be used with caution in patients suffering from diseases of the cardiovascular system (arterial hypertension, coronary heart disease, chronic heart failure, tachycardia, arrhythmias), impaired carbohydrate metabolism (diabetes mellitus), thyroid function (hyperthyroidism), pheochromocytoma, chronic renal failure, prostatic hyperplasia (urinary retention) and taking tricyclic antidepressants and bromocriptine.

Side effects

Sometimes burning or dryness of the nasal mucosa, dryness in the mouth and throat, sneezing, an increase in the volume of secretions released from the nose. In rare cases – after the effect of the drug has passed, a strong feeling of “stuffy” nose (reactive hyperemia). Side effects due to the systemic action of the drug: increased blood pressure, headache, dizziness, palpitations, tachycardia, increased anxiety, sedation, irritability, sleep disorders (in children), nausea, insomnia, exanthema, visual impairment (if in contact with the eyes). The preservative benzalkonium chloride, which is part of the drug, can cause swelling of the nasal mucosa. If this happens, you need to change the drug to another one that does not contain preservatives.

Interaction

When used concomitantly with MAO inhibitors (including a period of 14 days after their withdrawal) and tricyclic antidepressants, an increase in blood pressure may occur. The drug slows down the absorption of local anesthetics, prolongs their effect. Co-use of other vasoconstrictor drugs increases the risk of side effects.

How to take, course of use and dosage

Intranasally. Adults and children older than 10 years – 1-2 injections in each nasal passage maximum 2-3 times a day. Children from 6 to 10 years – 1 injection in each nasal passage, maximum 2-3 times a day. Duration of treatment: It is not recommended to use the drug for more than 7 days. With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms occur, you should stop treatment and consult a doctor. When injecting, do not tilt your head back or spray while lying down.

Overdose

Symptoms: nausea, high blood pressure, tachycardia, central nervous system depression. Treatment: symptomatic.

Special instructions

At the recommended dose, do not use for more than 7 days without consulting a doctor. If symptoms worsen or do not improve within 3 days, you should consult your doctor. Avoid contact with eyes. To avoid the spread of infection, it is necessary to use the drug individually.

Form of production

Nasal spray 0,05%.

Storage conditions

At a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 3 years.

Active ingredient

Oxymetazoline

Dosage form

nasal spray

Description

For adults and Children over 6 years of age

Indications

Sinusitis, Runny Nose, Flu, Allergic Runny Nose, Cold, Otitis