Wobenzyme pills, 40pcs

Composition

Active ingredients:  

Pancreatin 345 prot. Evr. Pharm. – Ed.,

papain 90 F. I. P-Ed.,

rutoside 3 H2O 50,00 mg,

bromelain 225 F. I. P-Ed.,

trypsin 360 F. I. P-Ed..

Lipase 34 F. I. P-Units..

amylase 50 F. I. P-Units,

chymotrypsin 300 F. I. P-Units.

Auxiliary substances:  

Lactose,

corn starch,

magnesium stearate,

stearic acid,

purified water,

colloidal silicon dioxide,

talc.

Sucrose,

talc,

methacrylic acid-methyl methacrylate copolymer,

shellac,

titanium dioxide,

white clay,

yellow-orange dye S (E 110),

red dye 4R (E 124),

povidone,

macrogol 6000,

triethyl citrate,

vanillin,

bleached

wax, Carnauba wax.

Pharmacological action

Combined drug. It is a combination of highly active enzymes of plant and animal origin. It has immunomodulatory, anti-inflammatory, fibrinolytic, decongestant, antiplatelet and secondary analgesic effects.

Wobenzym has a positive effect on the course of the inflammatory process, limits the pathological manifestations of autoimmune and immunocomplex processes, and positively affects the indicators of the body’s immunological reactivity. It stimulates and regulates the functional activity of monocytes-macrophages, natural killers, stimulates antitumor immunity, cytotoxic T-lymphocytes, and phagocytic cell activity.

Under the influence of Wobenzyme, the number of circulating immune complexes decreases and membrane deposits of immune complexes are removed from tissues.

Wobenzym reduces infiltration of the interstitium by plasma cells. Increases the elimination of protein detritus and fibrin deposits in the inflammatory zone, accelerates the lysis of toxic metabolic products and dying tissues; improves the resorption of hematomas and edema; normalizes the permeability of vascular walls.

Wobenzym reduces the concentration of thromboxane and platelet aggregation. Regulates the adhesion of blood cells, increases the ability of red blood cells to change their shape, regulating their plasticity; normalizes the number of normal discocytes (platelets) and reduces the total number of activated platelet forms, normalizes blood viscosity, reduces the total number of microaggregants, thus improving microcirculation and rheological properties of blood, as well as the supply of oxygen and nutrients to tissues.

Wobenzym normalizes lipid metabolism, reduces the synthesis of endogenous cholesterol, increases HDL, reduces the level of atherogenic lipids, and improves the absorption of polyunsaturated fatty acids.

Wobenzym increases the effectiveness of antibiotic therapy by increasing the concentration of antibiotics in the blood plasma and the focus of inflammation, and also reduces the side effects of antibiotics (dysbiosis).

Vobenzym reduces the severity of side effects associated with taking hormonal drugs (including hypercoagulation).

Wobenzym regulates the mechanisms of non-specific protection (production of interferons), thereby showing antiviral and antimicrobial effects.

The secondary analgesic effect of Wobenzyme is manifested through the influence on the causal factors of the acute inflammatory process.

Indications

For adults

As part of complex therapy:

• Thrombophlebitis (including acute superficial venous thrombophlebitis), postphlebitic syndrome, obliterating endarteritis and atherosclerosis of the lower extremities, lymphatic edema, prevention of recurrent phlebitis;
• Cystitis, cystopyelitis, prostatitis;
• Sexually transmitted infections;
• Chronic genital infections, gestosis, mastopathy, adnexitis, to reduce the frequency and severity of side effects of hormone replacement therapy in gynecology;
• Tension angina, subacute stage of myocardial infarction (to improve the rheological properties of blood);
• Sinusitis, bronchitis, and pneumonia.
• Pancreatitis, hepatitis;
• Pyelonephritis, glomerulonephritis;
• Diabetic angiopathy, diabetic retinopathy;
• Autoimmune thyroiditis;
• Rheumatoid arthritis, reactive arthritis, Ankylosing spondylitis;
• Atopic dermatitis, acne;
• Multiple sclerosis;
• Uveitis, iridocyclitis, hemophthalmos in ophthalmic surgery;
• Treatment of postoperative complications (inflammatory processes, thrombosis, edema), adhesions, post-traumatic and lymphatic edema, plastic and reconstructive operations;
• Injuries, fractures, distortions, dislocations, bruises, chronic post-traumatic processes, soft tissue inflammation, burns, injuries in sports medicine;
• rheumatoid arthritis;
• bronchitis, pneumonia;
• pancreatitis;
• atopic dermatitis;
• prevention of atherosclerosis.

Prevention

• Microcirculation disorders, post-stress disorders, as well as disruption of adaptive mechanisms;
• Side effects of hormone replacement therapy, hormonal contraception;
• Viral infections and their complications;
• Infectious complications and improved quality of life during chemotherapy or radiation therapy;
• During surgical interventions to prevent infectious complications and adhesions.

For children

As part of complex therapy:

• Atopic dermatitis;
• Infectious and inflammatory diseases of the respiratory tract (inflammation of the upper and lower respiratory tract, pneumonia);
• Juvenile rheumatoid arthritis.

Prevention and treatment of postoperative complications (infectious complications, poor wound healing, adhesions, local edema).

Use during pregnancy and lactation

With caution and under the supervision of a doctor, Vobenzym should be prescribed during pregnancy and lactation.

Contraindications

Diseases associated with an increased probability of bleeding (including hemophilia, thrombocytopenia); hemodialysis; children under 5 years of age;individual intolerance to the drug.

Side effects

Wobenzyme is generally well tolerated by patients. In most cases, side effects, withdrawal symptoms, and addiction were not observed even with long-term use in high doses.

In some cases:  minor changes in the consistency and smell of feces, urticaria (disappear when the dose is reduced or the drug is discontinued).

The patient should be warned that if other adverse reactions occur, it is recommended to stop taking the drug and consult a doctor.

Interaction

When taking Vobenzym with other medications at the same time, cases of incompatibility are unknown.

How to take, course of use and dosage

Set individually, depending on the severity of the disease.

Adults, depending on the activity and severity of the disease, are prescribed a dose of 3 to 10 tablets 3 times a day. In the first 3 days of taking the drug, the recommended dose is 3 tablets. 3 times / day.

With an average activity of the disease, the drug is prescribed at a dose of 5-7 tablets 3 times a day for 2 weeks. In the future, the dose of the drug should be reduced to 3-5 tab. 3 times / day. The course is 2 weeks.

If the disease is highly active, the drug is prescribed at a dose of 7-10 tablets 3 times a day for 2-3 weeks. In the future, the dose should be reduced to 5 tab. 3 times / day. Course – 2-3 months.

For chronic long-term diseases Wobenzym can be used as indicated in courses from 3 to 6 months or more.

To increase the effectiveness of antibiotics and prevent dysbiosis Vobenzym should be used throughout the entire course of antibiotic therapy at a dose of 5 tablets. 3 times / day. After stopping the course of antibiotic therapy to restore the intestinal microflora, Vobenzym should be prescribed 3 tablets 3 times a day for 2 weeks.

During radiation and chemotherapy Vobenzym should be used at a dose of 5 tablets 3 times / day until the end of the course of radiation and chemotherapy in order to prevent infectious complications, improve the tolerability of basic therapy and improve the quality of life.

For preventive purposes Vobenzym is prescribed 3 tablets 3 times / day for 1.5 months with a repetition of the course 2-3 times a year.

Children aged 5-12 years are prescribed a daily dose of 1 tablet per 6 kg of body weight. For children over 12 years of age, the drug is prescribed according to the scheme intended for adults. The duration of treatment is determined individually.

The drug should be taken at least 30 minutes before meals, without chewing, with water (200 ml).

Overdose

No cases of overdose of Vobenzym have been reported.

Special instructions

In the case of infectious processes, VOBENZYM does not replace antibiotics, but increases their effectiveness by increasing the concentration in the blood plasma and the focus of inflammation.

It should be borne in mind that at the very beginning of taking the drug, the symptoms of the disease may worsen, in such cases, treatment should not be interrupted, and a temporary reduction in the dose of the drug is recommended.

The drug is not doping and has no negative impact on driving a car and performing work that requires a high rate of mental and physical reactions.

Form of production

Tablets coated with an enteric-soluble shell of red-orange color, round, biconvex, with a smooth surface, with a characteristic smell; fluctuations in the intensity of color of the outer shell from red-orange to red are allowed.

Storage conditions

List B. The drug should be stored out of the reach of children, in a dry place at a temperature of 15° to 25°C.

Shelf

life is 2.5 years.

Active ingredient

Trypsin, Pancreatin, Rutoside, Chymotrypsin, Bromelain, Lipase, Amylase, Papain

Dosage form

Tablets

Purpose

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Adults, Children as prescribed by a doctor, Children over 5 years of age

Indications

Atherosclerosis, Rheumatoid Arthritis, Dermatitis, Hepatitis, Angina Pectoris, Bone Fractures, Pneumonia, Urinary Tract Infections, Thrombophlebitis, Respiratory Tract infections, Prostatitis, Swelling after injuries and operations, Myocardial infarction, Iridocyclitis, Acne, Burns, Diabetic Retinopathy