ATC code | A10BD07 |
---|---|
CAS Number | 1421445-82-9 (dapagliflozin) / 658-79-6 (metformin) |
Other product names | Xigduo XR, Dapagliflozin/Metformin, Jentadueto XR |
Dosage form | Film-coated tablet, extended release |
Active ingredient | Dapagliflozin / Metformin hydrochloride |
Other ingredients | Hypromellose, magnesium stearate, macrogol 3350, microcrystalline cellulose, povidone, sodium stearyl fumarate, talc, titanium dioxide, iron oxide yellow, iron oxide red, and iron oxide black |
Pharmacological classification | Antidiabetic agents, combinations |
Pharmacological action | Inhibits sodium-glucose cotransporter 2 (SGLT2) in the kidneys, leading to increased urinary glucose excretion and reduction of blood glucose levels. Metformin is a biguanide that reduces hepatic glucose production, improves insulin sensitivity, and decreases intestinal glucose absorption. |
Storage conditions | Store below 30°C (86°F). |
Xigduo XR: A Comprehensive Guide for Type 2 Diabetes
What is Xigduo XR?
Xigduo XR is a combination drug for adults with type 2 diabetes. It helps regulate blood sugar levels by combining two potent components: metformin, a biguanide, and dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor.
Xigduo XR’s Compositional Structure
Xigduo XR blends the strength of metformin with dapagliflozin. Dapagliflozin, an SGLT2 inhibitor, works in your kidneys to prevent the reabsorption of glucose back into your bloodstream. This allows your body to eliminate excess sugar naturally through urine. Think of it as your systems equivalent of a sugar drain.
Metformin, on the other hand, is a biguanide that helps your body use insulin more effectively. Insulin is a hormone that controls blood sugar levels. Metformin helps your cells absorb glucose more readily, thus reducing your blood sugar levels. Its like giving your cells a tiny push so they can utilize the energy they need.
Xigduo XR’s Advantages and Effects
Xigduo XR offers several potential benefits for managing type 2 diabetes. Some key advantages include:
- Improved blood sugar control: By working on the kidneys and your bodys response to insulin, Xigduo XR helps you achieve better blood sugar control. This is essential in preventing long-term diabetes complications.
- Lowered A1C levels: A1C measures your average blood sugar levels over the past few months. Xigduo XR can help reduce your A1C readings, indicating improved long-term blood sugar control.
- Weight management: Xigduo XR may promote modest weight loss, which can be beneficial for patients with type 2 diabetes, as weight loss often improves blood sugar control.
Xigduo XR’s Usage
Xigduo XR is indicated as an adjunct to diet and exercise to help individuals with type 2 diabetes better manage their glycemic load. While its not a cure for diabetes, it can be a helpful tool in your diabetic management regimen. It is typically used when diet and exercise alone are insufficient to regulate blood sugar levels.
How to Use Xigduo XR
Xigduo XR is usually taken once a day with the morning meal. It comes in tablet form. It is important to swallow the tablets whole; avoid crushing, chewing, or breaking them. This ensures proper release of the medication into your body. Always follow your doctors instructions carefully; never change your dosage unless advised.
Administration and Dosage
The dosage of Xigduo XR will depend on your medical history and individual needs. Your doctor will determine the appropriate dosage for you, which may change over time. It is crucial to avoid missing doses and take Xigduo XR exactly as directed.
Side Effects of Xigduo XR
Like any medication, Xigduo XR may have side effects. Some common side effects include:
- Nausea
- Diarrhea
- Vaginal yeast infections
- Increased urination
- Dehydration
If you experience any severe or persistent side effects, consult your doctor immediately. They can ensure your safe medication intake and help manage any adverse effects.
Contraindications of Xigduo XR
Xigduo XR is not suitable for everyone. It is contraindicated in certain cases, such as:
- Severe kidney disease
- Severe liver disease
- Diabetic ketoacidosis (a serious complication of diabetes)
- Severe heart failure
- Allergy to metformin or dapagliflozin
Before starting Xigduo XR, inform your doctor about your medical history, including any pre-existing conditions or medications you are taking.
Storage Environment for Xigduo XR
Store Xigduo XR at room temperature, between 68°F and 77°F (20°C and 25°C), in a dry place. Keep it out of reach of children and pets. Do not store Xigduo XR in the bathroom or in moist or humid environments. Do not use Xigduo XR after the expiration date printed on the bottle. If you have any questions about storing Xigduo XR, consult your pharmacist.
Important Information About Xigduo XR
Xigduo XR is an effective medication for managing your type 2 diabetes. It is crucial to follow your doctors advice closely and take it as directed. If you have any questions or concerns regarding Xigduo XR, consult your pharmacist or doctor. They are here to guide you in using this medication properly and effectively.
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Side effects of Xigduo XR tablets 5mg+1000mg, 60pcs
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