ATC code | L04AA06 |
---|---|
CAS Number | 211955-54-2 |
Other product names | Xolair |
Dosage form | Solution for injection in pre-filled syringe |
Active ingredient | Omalizumab |
Other ingredients | Sodium dihydrogen phosphate monohydrate, disodium phosphate dihydrate, sodium chloride, polysorbate 80, water for injections |
Pharmacological classification | Selective immunosuppressants |
Pharmacological action | Binds to immunoglobulin E (IgE), reducing free IgE, down-regulating high-affinity IgE receptors, limiting mast cell degranulation, minimizing the release of mediators throughout the allergic inflammatory cascade |
Storage conditions | Store in a refrigerator (2°C to 8°C). Do not freeze. |
Xolair: A Comprehensive Overview
Xolair is a prescription medication that treats moderate to severe persistent asthma in adults and children six years of age and older who have allergies to dust mites, mold, pollen, or pet dander. In adults and children 12 years of age and older whose symptoms have not been managed with antihistamines, Xolair is also used to treat chronic idiopathic urticaria (hives).
Xolair’s Composition
The active component in Xolair is the monoclonal antibody omalizumab. Monoclonal antibodies are proteins meant to target and inhibit particular bodily proteins. When it comes to Xolair, omalizumab targets and blocks immunoglobulin E (IgE), a protein linked to allergic responses.
Advantages and Results of Xolair
Blocking IgE from attaching to mast cells and basophils helps Xolair aid to lessen the symptoms of asthma and chronic urticaria. This stops histamine and other inflammatory mediators from being released, hence triggering allergic reactions. Xolair can thus aid in lowering hives frequency and intensity, as well as the frequency of asthma episodes.
Xolair is Recommended for
- In adults and children six years of age and above with allergies to dust mites, mold, pollen, or pet dander, moderate to severe chronic asthma
- In adults and children 12 years of age and older whose symptoms have not been under control with antihistamines, chronic idiopathic urticaria (hives).
How to Use Xolair
Xolair is injected under the skin—that is, subcutaneously. Your weight and degree of condition will determine the Xolair dosage you get. Your doctor will decide on your suitable dosage.
Xolair Dosage and Administration
- Xolair is advised to be taken 150 mg subcutaneously every two to four weeks for asthma.
- Xolair is advised to be taken 300 mg subcutaneously every 4 weeks for chronic idiopathic urticaria.
Adverse Effects of Xolair
Though not everyone experiences them, Xolair can have adverse effects, just as any medication. The most often occurring side effects of Xolair include:
- Injection site responses including redness, swelling, discomfort, or itching.
- Acute headache.
- Muscle pain.
- Joint soreness.
- P tiredness.
See your doctor if you run into any of these side effects.
Xolair: Contraindications
Not everyone will find Xolair suitable. Should you be allergic to omalizumab or any other component in Xolair, you should not take Xolair. Furthermore, avoid Xolair if you have a history of serious allergic reactions to any other monoclonal antibody.
Xolair’s Storage Environment
Store Xolair refrigerated between 2°C and 8°C. Steer clear of freezing. Keep Xolair out of youngsters grasp.
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Xolair: Obtain the Required Relief
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