Zalain, vaginal suppositories 300mg 1pc

Composition

Active ingredient:  

sertaconazole nitrate 300 mg,

excipients:

vitepsol,

suppocir,

colloidal anhydrous silicon dioxide.

Pharmacological action

Pharmacotherapeutic group:

antifungal agent

ATX code: G01AF

PHARMACOLOGICAL PROPERTIES

Sertaconazole is an antifungal agent derived from imidazole and benzothiophene. It has a fungistatic and fungicidal effect in therapeutic doses. Active against fungi of the genus Candida. The mechanism of action of sertaconazole is to inhibit the synthesis of ergosterol and increase the permeability of the cell membrane, which leads to lysis of the fungal cell. It also has antibacterial activity against gram-positive bacteria (staphylococci and streptococci).

PHARMACOKINETICS

There is no systemic absorption after intravaginal use. Unchanged sertaconazole is not detected in either blood plasma or urine.

Indications

Local treatment of infections of the vaginal mucosa caused by fungi of the genus Candida (candida vulvovaginitis).

Use during pregnancy and lactation

There are no sufficient data on the use of sertaconazole during pregnancy and lactation.

However, taking into account the method of use of the drug (single use), as well as the lack of systemic absorption of the drug after intravaginal use, the use of sertaconazole during pregnancy and lactation is possible if the potential benefit to the mother outweighs the possible risk to the fetus or child.

Contraindications

Hypersensitivity to imidazole derivatives, benzothiophene and other components of the drug.

Side effects

Rarely: burning sensation, itching in the vagina, which go away on their own during treatment and do not require discontinuation of the drug.

These side effects are classic for topical medications and reflect the effectiveness of the drug.

Possible allergic reactions.

Interaction

Concomitant use of the drug with local contraceptives may lead to a weakening of the spermicidal effect of the latter.

How to take, course of use and dosage

Intravaginally, once.

Before using the drug, it is necessary to wash the external genitalia using neutral or alkaline soap.

One vaginal suppository is inserted deep into the vagina, lying on your back, before going to bed.

If clinical symptoms persist, the suppository may be re-administered after 7 days.

Form of production

Suppositories are oval in shape, waxy, white in color.

Storage conditions

At a temperature not exceeding 30 °C.

Shelf life

3 years

Active ingredient

Sertaconazole

Dosage form

vaginal suppositories

Description

For adults, Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor

Indications

Thrush