Belosalic, ointment, 30g

Composition

>

of 1 g of ointment contains:

Active ingredients:

betamethasone dipropionate – 640 mcg, which corresponds to the content of betamethasone-500 mcg;

salicylic acid 30 mg.

Auxiliary substances:

mineral oil,

vaseline.

Pharmacological action

Pharmaceutical group:

glucocorticosteroid+keratolytic agent.

Pharmaceutical action:

Preparation for external use. Belosalic ® lotion has anti-inflammatory, antipruritic, decongestant, anti-allergic, antiproliferative, immunosuppressive, keratolytic, antimicrobial, antifungal effects.

Betamethasone dipropionate is a synthetic corticosteroid that has anti-inflammatory, anti-allergic, antipruritic and vasoconstrictor effects.

When applied to the skin surface, it narrows blood vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), interleukins 1 and 2, gamma interferon (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and lowers the permeability of the vascular wall.

It interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, which induces the formation of proteins, including lipocortin, mediating cellular effects. Lipocortin inhibits phospholipase A2, blocks the release of arachidonic acid and the biosynthesis of endoperoxides, prostaglandins, and leukotrienes (which contribute to the development of inflammation, allergies, and other pathological processes).

Salicylic acid due to its keratolytic action cleanses the affected areas from scales, promotes the penetration of betamethasone into the skin, supports the acidic environment of the skin, preventing the development of bacterial and fungal infections.

Indications

Subacute and chronic dermatoses, in which topical corticosteroid therapy is effective, and accompanied by hyperkeratosis and peeling, including:

• Psoriasis.
• Eczema (dyshidrotic, seborrheic, thylotic).
• Neurodermatitis.
• Red lichen planus.
• Asbestos-like lichen.
• Chronic discoid lupus erythematosus.
• Ichthyosis and ichthyotic skin lesions.
• Seborrhea.
• Seborrheic dermatitis (of the scalp).

The drug in the form of a solution for external use is indicated for use on the scalp, as well as in children 6 months and older.

Use during pregnancy and lactation

The use of the drug Belosalic (in the form of an ointment and / or solution for external use) in pregnant women is allowed in cases where the intended benefit to the mother exceeds the risk to the fetus.

In such cases, the use of the drug should be short and limited to small areas of the skin.

During breastfeeding, the use of the drug Belosalic is possible according to strict indications, but the drug should not be applied to the skin of the breast before feeding.

Contraindications

• Tuberculosis of the skin.
• Skin manifestations of syphilis.
• Chicken pox.
• Viral skin infections.
• Skin postvaccinal reactions.
• Open wounds.
• Trophic ulcers.
• Rosacea.
• Vulgar blackheads.
• Children under 6 months of age (for ointments).
• Hypersensitivity to betamethasone, salicylic acid or any of the auxiliary components of the drug.

Side effects

Side effects are usually mild in nature.

Dermatological reactions: hypersensitivity reactions (itching, burning, hyperemia) may occur; rarely-acne-like changes, hypopigmentation, striae, skin atrophy, hypertrichosis, telangiectasia, secondary skin infections.

With long-term continuous use and on large areas of the skin: betamethasone can cause systemic adverse reactions associated with suppression of the adrenal cortex.

If a hypersensitivity reaction or adverse reactions develop, the drug should be discontinued.

Interaction

There was no clinically significant interaction with other drugs.

The simultaneous use of cosmetic and dermatological products for the treatment of acne, products containing ethanol, or medical soaps with a pronounced drying effect, can in certain cases cause skin irritation.

How to take, course of use and dosage

The drug is intended for external use.

A small amount of ointment is evenly distributed over the surface of the skin, lightly rubbing. The frequency of application is 2 times / day, in mild cases, a single use is sufficient.

The duration of a continuous course of treatment is usually limited to 3-4 weeks. If you need a longer course of therapy, it is recommended to use the drug less often, for example, every other day. In the treatment of chronic diseases, treatment should be continued for some time after all symptoms disappear, under the supervision of a doctor, in order to avoid relapse of the disease.

Repeated courses of therapy are possible throughout the year.

Overdose

Symptoms: with prolonged continuous use of a combination of betamethasone and salicylic acid, especially in children, on large skin surfaces, when applied to skin with impaired integrity or when used under an occlusive dressing, increased absorption of active components and the manifestation of systemic effects (secondary adrenal insufficiency, hypercorticism, Itsenko-Cushing syndrome) are not excluded.

Treatment: Discontinuation of the drug and symptomatic therapy are recommended.

Special instructions

The ointment is intended only for external use on the skin and / or scalp.

Avoid contact with the ointment in the eyes and on the mucous membranes.

Long-term use of the ointment on the face is not recommended due to the possible development of rosacea-type dermatitis, perioral dermatitis, skin atrophy and acne.

The use of the drug in the anogenital area should be avoided.

It is not recommended to use the drug under an occlusal dressing, except when necessary. If fungal or bacterial microflora develops on the skin, additional use of an antibacterial or antifungal agent is necessary.

Use in pediatrics

The use of the drug Belosalic in children should be as short as possible with strict precautions, because in children there is a risk of systemic absorption of proportionally more active components due to the predominance of the skin area over body weight and insufficient maturity of the epidermis. Do not use the drug in children under bandages and, especially, under plasticized diapers, which may increase the risk of adverse events.

Influence on the ability to drive motor vehicles and manage mechanisms

There are no data on the adverse effects of Belosalic on the ability to drive vehicles and mechanisms.

Form of production

Ointment for external use.

Storage conditions

Keep out of reach of children at a temperature not exceeding 25°C.

Shelf

life is 4 years.

Active ingredient

Betamethasone, Salicylic Acid

Dosage form

ointment

Description

Children as prescribed by a doctor, Children over 6 months of age, Adults, Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor

Indications

Urticaria, Psoriasis, Allergies, Dermatosis, Dermatitis, Eczema, Neurodermatitis