Composition
100 g of cream contains:
- Active ingredient-zinc pyrithione (in terms of 100% substance) – 0.2 g (0.2%);
excipients:
- macrogol cetostearate,
- cetostearyl alcohol,
- liquid paraffin (petroleum jelly oil),
- propylene glycol, dexpanthenol (D-Panthenol),
- sodium dihydrogen phosphate dihydrate,
- sodium hydrophosphate dodecahydrate,
- purified water.
Pharmacological action
Pyrithione zinc has anti-inflammatory, antibacterial and antifungal activity. The antibacterial activity of zinc pyrithione is manifested against a number of gram-positive and gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp. )Â
Zinc pyrithione reduces the intracellular level of ATP, promotes depolarization of cell membranes, causing the death of fungi and bacteria. Antifungal activity is particularly pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare), which cause inflammation and excessive peeling in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action has not been studied.
Pharmacokinetics
Systemic absorption is negligible. The drug is found in the blood in trace amounts.
Indications
-
Psoriasis
-
atopic dermatitis (eczema, atopic dermatitis)
-
seborrheic dermatitis
- dry skin
Contraindications
Hypersensitivity, children under 1 year of age.
Side effects
The drug is usually well tolerated.
Sometimes there are allergic reactions.
How to take, course of use and dosage
The drug is intended for external use.
Apply in adults and children from 1 year.
The cream is applied in a thin layer on the affected areas 2-3 times a day.
Duration of treatment for:
- psoriasis-1-1.5 months, repeated courses-if signs of exacerbation appear;
- atopic dermatitis-3-4 weeks;
- seborrheic dermatitis-2 weeks.
Form of production
Cream for external use
Storage conditions
In a dry place, at a temperature of 4-25 °C
Shelf life
2 years
Active ingredient
Pyrithione zinc
Dosage form
cream
Description
Nursing mothers as prescribed by a doctor, For adults, Pregnant women as prescribed by a doctor, Children over 1 year old
Indications
Psoriasis, Dermatitis, Neurodermatitis, Eczema
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Side effects of Cinocap, cream 0,2%, 50g.
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