Combilipen pills, 30pcs

Composition

Active ingredients:

Benfotiamine-100 mg

Pyridoxine hydrochloride-100 mg

Cyanocobalamin-2 mcg

Excipients (core):

Sodium carmellose – 4,533 mg,

povidone-K 30-16,233 mg,

microcrystalline cellulose-12,673 mg,

talc – 4,580 mg,

calcium stearate-4,587 mg,

polysorbate-80-0,660 mg,

sucrose-206,732 mg.

Excipients (shell):

Hypromellose – 3,512 mg,

macrogol-4000-1,411 mg,

povidone low molecular weight-3,713 mg,

titanium dioxide-3,511 mg,

talc-1,353 mg

Pharmacological action

Pharmacotherapy group: multivitamin agent. ATX code: [A11AB]Pharmacological properties

Combined multivitamin complex. The effect of the drug is determined by the properties of the vitamins that make up its composition.

Benfotiamine is a fat-soluble form of thiamine (vitamin B-1). Participates in conducting a nerve impulse.

Pyridoxine hydrochloride (vitamin B6) – participates in the metabolism of proteins, carbohydrates and fats, is necessary for normal hematopoiesis, the functioning of the central and peripheral nervous system.

It provides synaptic transmission, inhibition processes in the central nervous system, participates in the transport of sphingosine, which is part of the nerve sheath, and participates in the synthesis of catecholamines.

Cyanocobalamin (vitamin B12) – participates in the synthesis of nucleotides, is an important factor in the normal growth, hematopoiesis and development of epithelial cells; it is necessary for folic acid metabolism and myelin synthesis.

Indications

It is used in the complex therapy of the following neurological diseases:

• trigeminal neuralgia;
• facial neuritis;
• pain syndrome caused by diseases of the spine (intercostal neuralgia, lumboschialgia, lumbar syndrome, cervical syndrome, cervical-brachial syndrome, radicular syndrome caused by degenerative changes of the spine).
• polyneuropathy of various etiologies (diabetic, alcoholic).

Use during pregnancy and lactation

Combilipen ® tabs contains 100 mg of vitamin B6 and therefore it is not recommended to use the drug in these cases.

Contraindications

Hypersensitivity to the components of the drug, severe and acute forms of decompensated heart failure, childhood.

Side effects

Allergic reactions (pruritus, urticular rash), in some cases increased sweating, nausea, tachycardia.

Interaction

Levodopa reduces the effect of therapeutic doses of vitamin B6. Vitamin B12 is incompatible with heavy metal salts. Ethanol dramatically reduces the absorption of thiamine. While taking the drug, it is not recommended to take multivitamin complexes that include B vitamins.

How to take, course of use and dosage

Tablets should be taken after a meal, without chewing and with a small amount of liquid. Adults: 1 tablet 1-3 times a day. Duration of the course – according to the doctor’s recommendation. Treatment with high doses of the drug for more than 4 weeks is not recommended.

Overdose

Symptoms: increased side effects of the drug.

First aid: gastric lavage, taking activated charcoal, prescribing symptomatic therapy.

Description

Round biconvex tablets, film-coated, white or almost white in color.

Form of production

Film-coated tablets. 15 tablets each in a contour cell pack. 1,2,3 or 4 contour cell packages together with instructions for medical use are placed in a pack of cardboard.

Storage conditions

At a temperature not exceeding 25 ° C. Keep out of reach of children.

Shelf

life is 2 years. Do not use after the expiration date.

Active ingredient

Multivitamins

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Indications

Lumbago, Trigeminal Neuralgia, Sciatica, Neuritis, Polyneuropathy, Sciatica