Cytovir-3, powder for preparation of solution 20g

Composition

Composition (per 1 ml of the finished solution):

Active ingredients:

alpha-glutamyl-tryptophan sodium 0.15 mg;

ascorbic acid 12 mg;

bendazole hydrochloride 1.25 mg.

Auxiliary substances:

fructose – 386.6 mg

Pharmacological action

The drug is a means of etiotropic and immunostimulating therapy, has an indirect antiviral effect against influenza A and B viruses and other viruses that cause acute respiratory viral diseases.

Bendazole induces the production of endogenous interferons in the body, has a moderate immunostimulating activity, which is associated with the regulation of the ratio of cGMP and cAMP concentrations in immune cells (increases the content of cGMP), which leads to the proliferation of mature sensitized T and B lymphocytes, their secretion of mutual regulation factors, cooperative reaction and activation of the final effector function of cells. Enzymes, the production of which is induced by interferons in cells of various organs, inhibit the replication of viruses.

Alpha-glutamyl-tryptophan (thymogen) is a synergist of the immunomodulatory action of bendazole, normalizing the T-cell link of immunity. Ascorbic acid normalizes capillary permeability, inhibits the formation of Pg and other inflammatory mediators, thereby reducing inflammation, and exhibits antioxidant properties, neutralizing oxygen radicals that accompany the inflammatory process, and increases the body’s resistance to infection.

Indications

Prevention and complex therapy of influenza and acute respiratory viral infections:

• for adults and children over 1 year old.

Contraindications

• diabetes mellitus;
• pregnancy;
• children under 1 year of age;
• hypersensitivity to the components of the drug.

With caution: during breastfeeding, use is possible if the intended benefit to the mother exceeds the potential risk to the child.

Side effects

From the cardiovascular system: short-term decrease in blood pressure.

Allergic reactions: rarely – urticaria (in such cases, the use of the drug is discontinued and symptomatic treatment, antihistamines are prescribed).

Interaction

Interactions of alpha-glutamyl-tryptophan with drugs were not detected.

Bendazole prevents an increase in OPSS due to non-selective beta-blockers. Increases the antihypertensive effect of antihypertensive and diuretic drugs. Phentolamine enhances the hypotensive effect of bendazole.

Ascorbic acid increases the concentration of benzylpenicillin and tetracyclines in the blood. Improves intestinal absorption of iron supplements. Reduces the effectiveness of heparin and indirect anticoagulants. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drinks reduce its absorption and assimilation.

When used concomitantly with ASA, the urinary excretion of ascorbic acid increases and the excretion of ASA decreases. ASA reduces the absorption of ascorbic acid by about 30%. Ascorbic acid increases the risk of crystalluria in the treatment of short-acting salicylates and sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood.

When used concomitantly, it reduces the chronotropic effect of isoprenaline. Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants. Barbiturates and primidone increase the excretion of ascorbic acid in the urine.

How to take, course of use and dosage

The drug is taken orally 30 minutes before meals.

The schemes of therapeutic and preventive use are identical.

Children aged 1 to 3 years – 2 ml of syrup 3 times a day.

Children aged 3 to 6 years – 4 ml 3 times / day.

Children aged 6 to 10 years – 8 ml 3 times / day.

Children over the age of 10 years – 12 ml 3 times / day.

The course of prevention or treatment is 4 days.

If necessary, the course of prevention is repeated in 3-4 weeks.

Rules for the preparation of a solution for oral use

Add 40 ml of water (boiled, cooled to room temperature) to the powder bottle and shake well. The contents should completely dissolve. The volume of the solution after adding water is 50 ml

Overdose

Cases of overdose of Cytovir®-3 are not described.

Special instructions

For repeated courses, monitoring of blood glucose levels is recommended.

Influence on the ability to drive motor vehicles and manage mechanisms

The drug does not affect the ability to drive vehicles and other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Powder for preparation of an oral solution

Storage conditions

store in a dry place at a temperature not exceeding 25°C. Keep out of reach of children. Store the prepared solution in a place protected from light at a temperature of 0 to 8° C.

Shelf

life is 3 years. Do not use after the expiration date indicated on the package. The shelf life of the prepared solution is 10 days.

Active ingredients

: Alpha-Glutamyl, Tryptophan, Ascorbic acid, Bendazole

Description

Children over 1 year old

Indications

Cold, Flu, Flu and cold prevention