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Belosalic, ointment, 30g
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Enzymes, Stomach, intestines, liver
Research Based Steps To Good Digestive Function
19
Feb
Feb
Maintaining a healthy digestive system is crucial for overall well-being and quality of life. The digestive system plays a vital role in breaking down food, absorbing essential nutrients, and eliminating waste from the body. However, many people experience digestive issues such as bloating, constipation, diarrhea, and abdominal discomfort, which can significantly impact their daily activities and lead to more severe health problems if left untreated.
Research has shown that adopting certain lifestyle habits and dietary modifications can greatly improve digestive function and alleviate common gastrointestinal symptoms. By understanding the intricacies of the digestive system and implementing evidence-based strategies, individuals can take proactive steps to optimize their digestive health and prevent the onset of chronic digestive disorders. This article will explore the latest research findings and provide practical tips for achieving and maintaining optimal digestive function.
Understanding the Digestive System
The digestive system is a complex network of organs that work together to break down food, absorb nutrients, and eliminate waste. The digestive tract, also known as the gastrointestinal (GI) tract, begins at the mouth and ends at the anus, spanning approximately 30 feet in length[1]. Along this journey, food undergoes various mechanical and chemical processes that enable the body to extract essential nutrients and energy.
Anatomy of the Digestive Tract
The major organs of the digestive system include the mouth, esophagus, stomach, small intestine, large intestine (colon), rectum, and anus. Accessory organs such as the liver, gallbladder, and pancreas also play crucial roles in digestion by producing enzymes and bile that aid in breaking down food[2].
Functions of the Digestive Organs
Each digestive organ has a specific function in the process of digestion. The mouth initiates the mechanical breakdown of food through chewing and the chemical breakdown through salivary enzymes. The esophagus transports food to the stomach, where it is further broken down by stomach acid and enzymes. The small intestine is responsible for the majority of nutrient absorption, while the large intestine absorbs water and forms solid waste. The liver, gallbladder, and pancreas produce and store essential digestive secretions[3].
Note
The digestive system is constantly working to process the food we eat and provide our bodies with the nutrients needed to function optimally.
Role of Digestive Enzymes and Hormones
Digestive enzymes, such as amylase, lipase, and proteases, are essential for breaking down carbohydrates, fats, and proteins, respectively. These enzymes are produced by various digestive organs, including the salivary glands, stomach, pancreas, and small intestine. Hormones, such as gastrin, secretin, and cholecystokinin, regulate the production and release of digestive enzymes and other secretions.
Common Digestive Disorders
Digestive disorders can range from mild to severe and can significantly impact an individual’s quality of life. Some common digestive disorders include:
- Gastroesophageal reflux disease (GERD)
- Irritable bowel syndrome (IBS)
- Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis
- Celiac disease
- Gallstones and gallbladder disorders
Understanding the anatomy and physiology of the digestive system is crucial for identifying and managing digestive disorders and maintaining optimal digestive health.
Maintaining a Balanced Diet
A well-balanced diet is essential for maintaining optimal digestive health. The foods we consume directly impact the functioning of our digestive system, and making informed dietary choices can help prevent and manage various digestive disorders[4].
Importance of a Well-Balanced Diet
A balanced diet provides the body with the necessary nutrients, including carbohydrates, proteins, fats, vitamins, and minerals, to support digestive health. Consuming a variety of nutrient-dense foods from all food groups ensures that the digestive system receives the building blocks it needs to function properly.
Important
Eating a balanced diet rich in whole foods and limiting processed foods can significantly improve digestive health and overall well-being.
Macronutrients: Carbohydrates, Proteins, and Fats
Macronutrients are the primary energy sources for the body and play crucial roles in digestive health. Complex carbohydrates, such as those found in whole grains, fruits, and vegetables, provide fiber and promote regular bowel movements. Lean proteins, including poultry, fish, and legumes, are essential for building and repairing tissues in the digestive tract. Healthy fats, such as those found in avocados, nuts, and olive oil, help absorb fat-soluble vitamins and support overall digestive function[5].
Micronutrients: Vitamins and Minerals
Vitamins and minerals are essential micronutrients that support various aspects of digestive health. For example, vitamin C aids in collagen production, which is necessary for maintaining the integrity of the digestive tract lining. Vitamin D helps the body absorb calcium, which is important for muscle function in the digestive system. Minerals such as magnesium and potassium play roles in regulating digestive enzymes and muscle contractions.
Fiber: Soluble and Insoluble
Fiber is a crucial component of a balanced diet and is essential for maintaining digestive health. Soluble fiber, found in foods such as oats, apples, and legumes, dissolves in water and forms a gel-like substance that helps regulate digestion and promotes feelings of fullness. Insoluble fiber, found in foods such as whole wheat, nuts, and vegetables, adds bulk to the stool and promotes regular bowel movements[6].
Hydration and Its Impact on Digestion
Adequate hydration is essential for maintaining optimal digestive function. Water helps dissolve nutrients, softens stool, and facilitates the passage of waste through the digestive tract. Consuming sufficient water throughout the day can help prevent constipation and promote regular bowel movements.
| Carbohydrates | Proteins | Fats | |
|---|---|---|---|
| Percentage of Total Calories | 45-65% | 10-35% | 20-35% |
Lifestyle Modifications for Better Digestion
In addition to maintaining a balanced diet, making certain lifestyle modifications can significantly improve digestive health and alleviate common gastrointestinal symptoms. Small changes in daily habits can have a profound impact on the functioning of the digestive system[7].
Regular Exercise and Physical Activity
Engaging in regular physical activity has been shown to promote digestive health by stimulating intestinal motility and reducing inflammation. Moderate-intensity exercises, such as brisk walking, cycling, and swimming, can help alleviate constipation, bloating, and other digestive discomforts. Aim for at least 30 minutes of physical activity most days of the week to support optimal digestive function[8].
Tip
Incorporating yoga and other relaxation techniques into your daily routine can help reduce stress and improve digestive health.
Stress Management Techniques
Chronic stress can have a negative impact on digestive health, leading to symptoms such as abdominal pain, bloating, and altered bowel habits. Implementing stress management techniques, such as deep breathing exercises, meditation, and progressive muscle relaxation, can help reduce stress levels and promote relaxation of the digestive tract. Engaging in stress-reducing activities, such as hobbies or spending time in nature, can also have a positive impact on digestive health.
Mindful Eating Practices
Mindful eating involves paying attention to the sensory aspects of food and being present in the moment while eating. This practice can help promote better digestion by encouraging slower eating, thorough chewing, and increased awareness of hunger and fullness cues. Mindful eating can also help reduce overeating and improve overall dietary choices[9].
Adequate Sleep and Rest
Getting sufficient sleep and rest is crucial for maintaining optimal digestive health. Sleep deprivation has been linked to increased inflammation and alterations in gut microbiota, which can contribute to digestive disorders. Aim for 7-9 hours of quality sleep per night and establish a consistent sleep schedule to support digestive health.
| Modification | Benefits |
|---|---|
| Regular Exercise | Stimulates intestinal motility, reduces inflammation |
| Stress Management | Reduces stress-related digestive symptoms |
| Mindful Eating | Promotes slower eating, better digestion |
| Adequate Sleep | Supports healthy gut microbiota, reduces inflammation |
By incorporating these lifestyle modifications into your daily routine, you can take proactive steps towards improving your digestive health and overall well-being.
Probiotics and Prebiotics
Probiotics and prebiotics have gained significant attention in recent years for their potential benefits in promoting digestive health. These compounds work together to support the growth and maintenance of beneficial gut bacteria, which play a crucial role in various aspects of digestive function[10].
Understanding Probiotics
Probiotics are live microorganisms that, when consumed in adequate amounts, can provide health benefits to the host. These beneficial bacteria are naturally found in fermented foods, such as yogurt, kefir, sauerkraut, and kimchi, and are also available as dietary supplements. The most common probiotic strains belong to the genera Lactobacillus and Bifidobacterium.
Probiotics can help maintain a healthy balance of gut bacteria, which is essential for optimal digestive function. They can also help alleviate symptoms associated with certain digestive disorders, such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Some studies suggest that probiotics may also support immune function and improve nutrient absorption[11].
The Role of Prebiotics
Prebiotics are non-digestible food components that serve as a substrate for the growth and activity of beneficial gut bacteria. These compounds are typically found in foods rich in complex carbohydrates, such as onions, garlic, leeks, asparagus, and whole grains. Prebiotics are also available as dietary supplements, often in the form of inulin or fructooligosaccharides (FOS).
Prebiotics promote the growth of beneficial gut bacteria, particularly Bifidobacteria and Lactobacilli, by providing them with a source of fermentable substrate. As these bacteria ferment the prebiotics, they produce short-chain fatty acids (SCFAs), such as butyrate, which have been shown to have anti-inflammatory properties and support the health of the gut lining[12].
Tip
Consuming a diet rich in both probiotics and prebiotics, known as a “synbiotic” approach, can provide synergistic benefits for digestive health.
Incorporating Probiotics and Prebiotics into Your Diet
To support digestive health through probiotics and prebiotics, consider incorporating the following foods and supplements into your diet:
- Fermented dairy products, such as yogurt and kefir
- Fermented vegetables, such as sauerkraut and kimchi
- Prebiotic-rich foods, such as onions, garlic, leeks, and asparagus
- Whole grains, such as oats and barley
- Probiotic and prebiotic supplements, under the guidance of a healthcare professional
By incorporating probiotics and prebiotics into your diet, you can support the growth and maintenance of beneficial gut bacteria, which can contribute to improved digestive health and overall well-being.
Physical Activity and Digestive Health
Regular physical activity is not only important for overall health and well-being but also plays a significant role in promoting digestive health. Engaging in exercise has been shown to have numerous benefits for the digestive system, including improving gut motility, reducing inflammation, and supporting the growth of beneficial gut bacteria[13].
Benefits of Exercise for Digestive Function
Exercise has been shown to stimulate intestinal motility, which can help alleviate symptoms of constipation and promote regular bowel movements. When we engage in physical activity, our abdominal muscles contract and relax, creating a massaging effect on the digestive organs. This can help move food and waste through the digestive tract more efficiently.
Additionally, exercise has been found to reduce inflammation in the body, including the digestive tract. Chronic inflammation has been linked to various digestive disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). By reducing inflammation through regular physical activity, we can help support the health and function of our digestive system[14].
Types of Exercise for Digestive Health
While any form of physical activity can be beneficial for digestive health, certain types of exercise may be particularly effective:
- Low-impact cardiovascular exercises, such as walking, swimming, and cycling, can help stimulate intestinal motility and reduce constipation.
- Core-strengthening exercises, such as planks and bridges, can help tone the abdominal muscles and support healthy digestion.
- Yoga and stretching exercises can help reduce stress and promote relaxation, which can have a positive impact on digestive function.
It is important to choose physical activities that you enjoy and can maintain consistently. Aim for at least 30 minutes of moderate-intensity exercise most days of the week for optimal digestive health benefits.
Important
Always listen to your body and consult with a healthcare professional before starting a new exercise routine, especially if you have pre-existing digestive issues or other health concerns.
Exercise and Gut Microbiome
Recent research has also highlighted the impact of exercise on the gut microbiome, the complex community of microorganisms that reside in our digestive tract. Studies have shown that regular physical activity can help support the growth and diversity of beneficial gut bacteria, such as Bifidobacteria and Lactobacilli[15].
A healthy gut microbiome is essential for optimal digestive function, immune support, and overall health. By engaging in regular exercise, we can help create a favorable environment for these beneficial microorganisms to thrive.
Incorporating regular physical activity into your lifestyle is a simple yet effective way to support digestive health. By engaging in a variety of exercises and listening to your body’s needs, you can help promote optimal digestive function and overall well-being.
Managing Digestive Symptoms
While maintaining a healthy diet, engaging in regular physical activity, and incorporating probiotics and prebiotics can help support digestive health, many individuals still experience occasional digestive symptoms. Learning how to manage these symptoms effectively can greatly improve quality of life and prevent minor issues from developing into more serious conditions[16].
Common Digestive Symptoms and Their Management
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Bloating and Gas: Bloating and gas can often be managed by identifying and avoiding trigger foods, such as those high in FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols). Eating smaller, more frequent meals and practicing mindful eating can also help reduce these symptoms. Over-the-counter digestive enzymes may provide relief for some individuals.
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Constipation: Constipation can be alleviated by increasing fiber intake, staying hydrated, and engaging in regular physical activity. In some cases, over-the-counter laxatives or stool softeners may be recommended by a healthcare professional. Establishing a regular bowel routine and avoiding prolonged periods of sitting can also help promote regular bowel movements.
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Diarrhea: Acute diarrhea can often be managed by staying hydrated, consuming electrolyte-rich fluids, and following a bland diet consisting of foods like bananas, rice, applesauce, and toast (BRAT diet). Probiotics, particularly those containing Lactobacillus rhamnosus GG and Saccharomyces boulardii, may help reduce the duration and severity of diarrhea[17]. Persistent or severe diarrhea should be evaluated by a healthcare professional.
Stress Management for Digestive Health
Stress can have a significant impact on digestive health, exacerbating symptoms like bloating, abdominal pain, and altered bowel habits. Incorporating stress management techniques into your daily routine can help alleviate stress-related digestive issues. Some effective strategies include:
- Deep breathing exercises
- Meditation and mindfulness practices
- Regular exercise and physical activity
- Engaging in hobbies and leisure activities
- Getting adequate sleep and rest
If stress is significantly impacting your digestive health, consider seeking support from a mental health professional who can provide additional coping strategies and guidance.
Important
If you experience persistent or severe digestive symptoms, it is essential to consult with a healthcare professional for proper evaluation and treatment. Some digestive issues may require medical intervention or be indicative of an underlying condition that needs addressing[18].
By understanding common digestive symptoms and employing effective management strategies, you can take control of your digestive health and minimize the impact of these issues on your daily life. Remember, small changes in diet, lifestyle, and stress management can make a significant difference in promoting optimal digestive function and overall well-being.
Diagnostic Tests and Procedures
When digestive symptoms persist or become severe, healthcare professionals may recommend various diagnostic tests and procedures to identify the underlying cause and develop an appropriate treatment plan. These tests can help evaluate the structure and function of the digestive system, as well as detect any abnormalities or diseases[19].
Common Diagnostic Tests for Digestive Health
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Stool Tests: Stool samples can be analyzed for the presence of blood, parasites, bacteria, or other abnormalities. These tests can help diagnose conditions like infections, inflammatory bowel disease (IBD), and colorectal cancer.
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Blood Tests: Blood tests can help evaluate liver and pancreatic function, detect anemia, and identify markers of inflammation or infection. Specific blood tests, such as celiac disease panels and food allergy tests, can also aid in diagnosing digestive disorders.
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Breath Tests: Breath tests are non-invasive procedures that can help diagnose conditions like small intestinal bacterial overgrowth (SIBO), lactose intolerance, and Helicobacter pylori infection.
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Imaging Tests: Imaging tests, such as X-rays, CT scans, MRIs, and ultrasounds, can provide detailed pictures of the digestive organs and help identify structural abnormalities, obstructions, or tumors.
Endoscopic Procedures for Digestive Health
Endoscopic procedures involve using a flexible tube with a camera and light source to visualize the inside of the digestive tract. These procedures can help diagnose and treat various digestive conditions[20]:
- Upper Endoscopy (EGD): This procedure examines the esophagus, stomach, and upper part of the small intestine (duodenum) to diagnose conditions like acid reflux, ulcers, and celiac disease.
- Colonoscopy: A colonoscopy allows visualization of the entire colon and rectum, helping to detect and remove precancerous polyps, diagnose IBD, and investigate the cause of chronic diarrhea or rectal bleeding.
- Capsule Endoscopy: This procedure involves swallowing a small, pill-sized camera that captures images of the digestive tract as it passes through, helping to diagnose conditions affecting the small intestine, such as Crohn’s disease and intestinal tumors.
Tip
Before undergoing any diagnostic test or procedure, discuss the risks, benefits, and preparation requirements with your healthcare provider. Following proper preparation instructions is crucial for accurate results and a successful procedure.
It is important to remember that diagnostic tests and procedures are just one aspect of a comprehensive digestive health evaluation. Healthcare professionals will also consider your medical history, physical examination findings, and response to treatment when making a diagnosis and developing a personalized care plan[21].
If you experience persistent or severe digestive symptoms, consult with your healthcare provider to determine which diagnostic tests or procedures may be appropriate for your specific situation. Early detection and intervention can help prevent complications and improve overall digestive health and well-being.
Implementing a Digestive Health Plan
Maintaining optimal digestive health requires a comprehensive approach that incorporates dietary modifications, lifestyle changes, and regular communication with healthcare professionals. By implementing a personalized digestive health plan, you can take proactive steps to support your digestive system and prevent or manage various gastrointestinal issues[22].
Set Realistic Goals and Prioritize Changes
When creating your digestive health plan, it is essential to set realistic goals and prioritize the changes you want to make. Start by focusing on one or two key areas, such as increasing your fiber intake or incorporating more physical activity into your daily routine. Gradual, sustainable changes are more likely to lead to long-term success than drastic, overwhelming modifications.
Keep a Food and Symptom Journal
Maintaining a food and symptom journal can be a valuable tool in identifying potential trigger foods and monitoring your body’s response to dietary changes. Record the foods you eat, along with any digestive symptoms you experience, such as bloating, gas, or abdominal discomfort. This information can help you and your healthcare provider identify patterns and make informed decisions about your digestive health plan.
Collaborate with Healthcare Professionals
Working closely with healthcare professionals, such as registered dietitians and gastroenterologists, can help ensure the success of your digestive health plan. These experts can provide personalized guidance on dietary modifications, recommend appropriate diagnostic tests or procedures, and monitor your progress over time. Regular check-ins and open communication with your healthcare team can help you stay on track and make adjustments as needed[23].
Practice Mindfulness and Stress Management
Incorporating mindfulness and stress management techniques into your digestive health plan can have a significant impact on your overall well-being. Practices such as deep breathing, meditation, and yoga can help reduce stress and promote relaxation, which may alleviate digestive symptoms exacerbated by stress. Make time for self-care activities and prioritize stress reduction in your daily life.
Be Patient and Consistent
Improving digestive health is a journey, and it is important to be patient and consistent with your efforts. It may take time for your body to adjust to dietary and lifestyle changes, and you may experience setbacks along the way. Stay committed to your digestive health plan, and remember that small, consistent steps can lead to significant improvements over time[24].
Important
Remember, everyone’s digestive health needs are unique. What works for one person may not work for another. Be open to adjusting your plan as needed and always listen to your body’s signals.
By implementing a personalized digestive health plan and working closely with healthcare professionals, you can take control of your digestive well-being and enjoy the benefits of a healthy, functioning digestive system. Stay motivated, celebrate your progress, and prioritize your digestive health as an integral part of your overall wellness journey.
Frequently Asked Questions
What are some common signs of digestive problems?
Common signs of digestive problems include abdominal pain, bloating, gas, constipation, diarrhea, heartburn, nausea, and vomiting. If you experience these symptoms persistently or if they interfere with your daily life, it’s essential to consult with a healthcare professional for proper evaluation and treatment.
How can I improve my digestive health naturally?
To improve your digestive health naturally, focus on consuming a balanced diet rich in fiber from fruits, vegetables, and whole grains. Stay hydrated by drinking plenty of water, engage in regular physical activity, and manage stress through relaxation techniques like deep breathing or meditation. Incorporating probiotics and prebiotics into your diet can also support a healthy gut microbiome.
What foods should I avoid for better digestive health?
To promote better digestive health, consider limiting or avoiding processed foods, high-fat foods, spicy foods, caffeine, and alcohol. Some individuals may also benefit from reducing their intake of fermentable carbohydrates (FODMAPs) or identifying and eliminating specific trigger foods through an elimination diet under the guidance of a healthcare professional.
Can stress affect my digestive health?
Yes, stress can have a significant impact on digestive health. Stress can exacerbate symptoms like bloating, abdominal pain, and altered bowel habits. Managing stress through techniques such as deep breathing, meditation, regular exercise, and engaging in hobbies or leisure activities can help alleviate stress-related digestive issues.
When should I see a doctor for digestive problems?
If you experience persistent or severe digestive symptoms, such as chronic abdominal pain, unexplained weight loss, blood in the stool, or difficulty swallowing, it is essential to consult with a healthcare professional promptly. Additionally, if your digestive issues interfere with your daily activities or quality of life, seeking medical advice can help identify the underlying cause and develop an appropriate treatment plan.
Are there any diagnostic tests for digestive disorders?
Yes, there are various diagnostic tests and procedures available to evaluate digestive health. These may include stool tests, blood tests, breath tests, imaging tests (such as X-rays, CT scans, or MRIs), and endoscopic procedures like upper endoscopy (EGD) or colonoscopy. Your healthcare provider will determine which tests are appropriate based on your specific symptoms and medical history.
How long does it take to see improvements in digestive health?
The time it takes to see improvements in digestive health varies from person to person. Some individuals may notice positive changes within a few days of implementing dietary and lifestyle modifications, while others may require several weeks or months to experience significant improvements. Consistency and patience are key when working towards better digestive health. If symptoms persist or worsen despite your efforts, consult with a healthcare professional for further guidance.
Reference list
Bibliography
- Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA. 2015;313(9):949-958.
- Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV. Gastroenterology. 2016;150(6):1262-1279.
- Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019;68(8):1516-1526.
- Rao SSC, Yu S, Fedewa A. Systematic review: dietary fibre and FODMAP-restricted diet in the management of constipation and irritable bowel syndrome. Aliment Pharmacol Ther. 2015;41(12):1256-1270.
- Hill C, Guarner F, Reid G, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014;11(8):506-514.
- Moayyedi P, Quigley EM, Lacy BE, et al. The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Am J Gastroenterol. 2014;109(9):1367-1374.
- Eswaran S, Muir J, Chey WD. Fiber and functional gastrointestinal disorders. Am J Gastroenterol. 2013;108(5):718-727.
- Cremonini F, Lembo A. Probiotics and irritable bowel syndrome. Dig Liver Dis. 2013;45 Suppl 5:S323-S326.
- Didari T, Mozaffari S, Nikfar S, Abdollahi M. Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis. World J Gastroenterol. 2015;21(10):3072-3084.
- Marsh A, Eslick EM, Eslick GD. Does a diet low in FODMAPs reduce symptoms associated with functional gastrointestinal disorders? A comprehensive systematic review and meta-analysis. Eur J Nutr. 2016;55(3):897-906.
- Staudacher HM, Whelan K. The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS. Gut. 2017;66(8):1517-1527.
- Moayyedi P, Andrews CN, MacQueen G, et al. Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS). J Can Assoc Gastroenterol. 2019;2(1):6-29.
- Oka P, Parr H, Barberio B, Black CJ, Savarino EV, Ford AC. Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2020;5(10):908-917.
- Black CJ, Ford AC. Global burden of irritable bowel syndrome: trends, predictions and risk factors. Nat Rev Gastroenterol Hepatol. 2020;17(8):473-486.
- Sperber AD, Bangdiwala SI, Drossman DA, et al. Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study. Gastroenterology. 2021;160(1):99-114.e3.
- Lacy BE, Pimentel M, Brenner DM, et al. ACG Clinical Guideline: Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2021;116(1):17-44.
- Ford AC, Sperber AD, Corsetti M, Camilleri M. Irritable bowel syndrome. Lancet. 2020;396(10263):1675-1688.
- Mearin F, Lacy BE, Chang L, et al. Bowel Disorders. Gastroenterology. 2016;150(6):1393-1407.e5.
- Menees SB, Powell C, Kurlander J, Goel A, Chey WD. A meta-analysis of the utility of C-reactive protein, erythrocyte sedimentation rate, fecal calprotectin, and fecal lactoferrin to exclude inflammatory bowel disease in adults with IBS. Am J Gastroenterol. 2015;110(3):444-454.
- Smalley W, Falck-Ytter C, Carrasco-Labra A, Wani S, Lytvyn L, Falck-Ytter Y. AGA Clinical Practice Guidelines on the Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D). Gastroenterology. 2019;157(3):851-854.
- Spiegel BM, Farid M, Esrailian E, Talley J, Chang L. Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts. Am J Gastroenterol. 2010;105(4):848-858.
- Ford AC, Lacy BE, Talley NJ. Irritable Bowel Syndrome. N Engl J Med. 2017;376(26):2566-2578.
- Simrén M, Törnblom H, Palsson OS, et al. Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts. Gut. 2018;67(2):255-262.
- Keefer L, Palsson OS, Pandolfino JE. Best Practice Update: Incorporating Psychogastroenterology Into Management of Digestive Disorders. Gastroenterology. 2018;154(5):1249-1257.
